cholinergic agonist

Question 1

Choose the ONE best answer.
4.1 Botulinum toxin blocks the release of acetylcholine from
cholinergic nerve terminals. Which of the following is a possible effect of botulinum toxin?

Answer 1

A. Skeletal muscle paralysis.

Question 2

4.2 A dentist would like to reduce salivation in a patient in
preparation for an oral surgical procedure. Which of the
following strategies will be useful in reducing salivation?

Answer 2

D. Block muscarinic receptors in the salivary glands.

Question 3

4.3 Which of the following is a systemic effect of a
muscarinic agonist?

Answer 3

A. Reduced heart rate (bradycardia).

Question 4

4.4 If an ophthalmologist wants to dilate the pupils for an
eye examination, which of the following drugs/classes
of drugs could be theoretically useful?
.

Answer 4

B. Muscarinic receptor inhibitor (antagonist).

Question 5

4.5 In Alzheimer’s disease, there is a deficiency of cholinergic neuronal function in the brain. Theoretically, which of the following strategies will be useful in treating the symptoms of Alzheimer’s disease?

Answer 5

C. Inhibiting the acetylcholinesterase enzyme in the brain.

Question 6

4.6 An elderly female who lives in a farm house was brought
to the emergency room in serious condition after ingesting a liquid from an unlabeled bottle found near
her bed, apparently in a suicide attempt. She presented
with diarrhea, frequent urination, convulsions, breathing difficulties, constricted pupils (miosis), and excessive salivation. Which of the following is correct regarding
this patient?

Answer 6

A. She most likely consumed an organophosphate
pesticide.

Question 7

4.7 Sarin is a volatile nerve agent that inhibits cholinesterase
enzymes. Which of the following symptoms would you
expect to see in a patient exposed to sarin?

Answer 7

C. Constriction of pupils (miosis)

Question 8

4.8 Head and neck irradiation in cancer patients can
decrease salivary secretion and cause dry mouth. All of
the following drugs or classes of drugs are theoretically
useful in improving secretion of saliva in these patients
except:

Answer 8

A. Muscarinic antagonists

Question 9

4.9 Which of the following drugs or classes of drugs will be
useful in treating the symptoms of myasthenia gravis?

Answer 9

D. Anticholinesterase agents

Question 10

4.10 Atropa belladonna is a plant that contains atropine (a
muscarinic antagonist). Which of the following drugs or
classes of drugs will be useful in treating poisoning with
belladonna?

Answer 10

B. Physostigmine