Cholinergic Flashcards

1
Q

Acetylcholine

A

Direct-acting cholinomimetic

Most rapid

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2
Q

Bethanechol

A

Direct-acting cholinomimetic

Least rapid

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3
Q

Cevimeline

A

Direct-acting cholinomimetic

Targets M3 receptors and is used for Sjogren’s syndrome (dry eyes + mouth)

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4
Q

Pilocarpine

A

Direct-acting cholinomimetic

Uncharged

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5
Q

Varenicline (Chantix)

A

Direct-acting cholinomimetic

Targets nicotinic receptors and is approved for smoking cessation.

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6
Q

Donepezil

A

Cholinesterase inhibitor

Uncharged - will go to CNS

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7
Q

Edrophonium

A

Cholinesterase inhibitor

Positively charged and reversible

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8
Q

Neostigmine

A

Cholinesterase inhibitor

Positively charged and reversible

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9
Q

Physostigmine

A

Cholinesterase inhibitor

Uncharged - will go to CNS

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10
Q

Pralidoxime

A

Cholinesterase regenerator

Used in addition to atropine to combat cholinergic poisoning

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11
Q

Scopolamine

A

Antimuscarinic drug

Used for motion sickness and in ophthalmology

Can cause drowsiness and amnesia

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12
Q

Atropine

A

Antimuscarinic drug

Used for GI disorders and in ophthalmology

Non-selective muscarinic antagonist

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13
Q

Glycopyrrolate

A

Antimuscarinic drug

Used for GI disorders

Charged

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14
Q

Tropicamide

A

Antimuscarinic drug

Used in ophthalmology

Uncharged - can enter CNS

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15
Q

Ipratropium

A

Antimuscarinic drug

Used for respiratory disorders

Charged

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16
Q

Tiotropium

A

Antimuscarinic drug

Used for respiratory disorders

17
Q

Darifenacin

A

Antimuscarinic drug

Used for urinary disorders

18
Q

Oxybutynin

A

Antimuscarinic drug

Used for urinary disorders

19
Q

Benztropine

A

Antimuscarinic drug

Used for movement disorders

Uncharged - can enter the CNS

20
Q

Mecamylamine

A

Ganglion blockers

Can cause sedation