Adrenergic Flashcards

1
Q

Epinephrine

A

Direct acting agonist

Beta 2 activation with Epi is&raquo_space; NE

Not orally effective

Used for asthma, anaphylactic shock, glaucoma, local anesthetics, cardiac resuscitation

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2
Q

Norepinephrine (Levophed)

A

Direct acting agonist A1, A2, B1

Vasoconstriction

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3
Q

Dopamine

A

Direct acting agonist

D1>a,b

Increases blood flow to kidneys

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4
Q

Phenylephrine

A

Alpha 1 agonist

Used for nasal decongestants, pressor, inducing bradycardia, glaucoma

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5
Q

Isoproterenol

A

Beta agonist

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6
Q

Dobutamine

A

Beta 1 agonist

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7
Q

Albuterol

A

Beta 2 agonist

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8
Q

Salmeterol

A

Beta 2 agonist

Long lasting - used at night

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9
Q

Formoterol

A

Beta 2 agonist

Long lasting - used at night

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10
Q

Midodrine

A

Alpha 1 agonist

Taken orally to stop orthostatic hypotension

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11
Q

Terbutaline

A

Beta 2 agonist

Can be taken orally

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12
Q

Amphetamines

A

Release NE from nerve endings and block its re-uptake

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13
Q

Clonidine

A

Alpha 2 agonist

Sudden withdrawal causes hypertensive crisis

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14
Q

Phentolamine

A

Alpha blocker

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15
Q

Prazosin

A

Alpha 1 blocker

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16
Q

Propranolol

A

Beta blocker

~25% bioavailability - titrate up for the patient as everyone is different

Sudden withdraw syndrome

17
Q

Atenolol

A

Beta 1 blocker

18
Q

Metoprolol

A

Beta 1 blocker

19
Q

Esmolol

A

Beta 1 blocker

Very short acting

20
Q

Labetalol

A

Alpha and beta blocker

21
Q

Carvedilol

A

Alpha and beta blocker

Used in CHF cases

22
Q

Phenoxybenzamine

A

Alpha blocker

Non-competitive irreversible

Used for Pheochromocytomas, peripheral vascular disease, raynaud’s syndrome, acrocyanosis

23
Q

Terazosin

A

Alpha 1 blocker

Used in the treatment of BPH

24
Q

Doxazosin

A

Alpha 1 blocker

25
Q

Tamulosin

A

Alpha 1A blocker - used against BPH but not as a vasodilater

26
Q

Reserpine

A

Depletes NE by blocking vesicular transporter

27
Q

Methyldopa

A

False neurotransmitter

Is stored in vesicles instead of NE

Used to treat hypertension in pregnant females

28
Q

Guanabenz and Guanfacine

A

Alpha 2 agonist