Chlamydia & Chlamydophila Flashcards
diagnosis of Chlamydia
trachomatis
Obligate intracellular, similar to gram (-)
test:
1)NAATs,
2)PCR to differentiate LGV from
non-LGV
*LGV: Lymphogranuloma venereum
infection route of Chlamydia
trachomatis
- Eye-eye transmission (droplet, hands, contaminated clothing, flies)
-STD
patho of Chlamydia
trachomatis
initial infection self limited, reinfection or superimposed bacterial conjunctivitis cause problems
the 2 biovers of Chlamydia Tarchomatis
trachoma & lymphogranuloma venereum
CM of Trachoma
acute follicular conjunctivitis (A-C serovars) initially —> papillary hypertrophy, inflammatory infiltration. Scarring of tarsal conjunctiva –> eyelashes turning in –> trichiasis –> corneal ulceration, scarring & opacification
CM of Trachoma (serovars D-K)
1) Inclusion conjuctivitis
–> Acute follicular conjuctivities w/ mucopurulent disharge, Keratitis, not responding to topical abx
2) Urogenital infections in men
Major cause of –> symptomatic non- gonococcal urethritis (NGU)
COMPLICATIONS?
epididymitis, prostatitis, proctitis
3) Urogenital infections in women (70% are asymptomatic)
- cervicitis, urethritis–> mucopurulent vaginal discharge, bleeding, mild abdominal pain,
dysuria, acute urethritis,
- pelvic inflammatory disease
4) Neonants
- inclusion conjunctivitis,
- PNeumonia, if >2y/o consider child sexual abuse
CM of Lymphogranuloma venerum biover of Chlamydia
trachomatis
(serovars L1-L3)
SELF-LIMITED painless ulcer , heals w/ No scar, tender inguinal adenopathy,
Rectal exposure- proctocolitis–> can be invasive w/ colorectal fistulas/strictures
infection route of Chlamydia Pneumonia
respiratory secretions
CM of Chlamydia
pneumoniae
Atypical Pneumonia
(w/low grade fever, non-prodictive coungh, self-limited)
Transmission of Chlamydia psittaci
BIRDS
CM of Chlamydia Psittaci
KA: “Bird flu- Parrot fever-ornithosis”
Atypical Pneumonia
sever Typhoid form–> fever , braychardia, splenomegaly
Diagnosis of Chlamydia Psittaci
DO NOT use culture –> dangerous
–> Serology
