Chlamydia / Chlamydophila Flashcards

1
Q

Two (2) species that are previously under
Chlamydia but became Chlamydophila.

A
  1. Chlamydophila pneumoniae
  2. Chlamydophila psittacci
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2
Q

Chlamydia/Chlamydophila are sensitive to what type of drugs?

A

Sulfa drugs

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3
Q

Chlamydia/Chlamydophila are what type of organisms?

A

Obligate intracellular organisms

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4
Q

Two (2) distinct forms of Chlamydia/Chlamydophila

A
  1. Elementary body
  2. Reticulated body
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5
Q

A distinct form of Chlamydia that is Infectious, has spore-like features, extracellular, and metabolically inert.

A

Elementary body

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6
Q

A distinct form of Chlamydia that is non-infectious, replicative form, and intracellular.

A

Reticulated body

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6
Q

What is the prominent component of membrane found in the Elementary body that contributes to the resistance to environmental/
physical stress?

A

Major Outer Membrane Protein (MOMP)

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7
Q

Two (2) shapes of Elementary body

A
  1. Round
  2. Pear-shaped
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8
Q

Chlamydia/Chlamydophila spp. that has/have ROUND elementary body

A

C. trachomatis
C. psittaci

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9
Q

Chlamydia/Chlamydophila spp. that has/have PEAR-SHAPED elementary body

A

C. pneumoniae

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10
Q

What are the disease C. trachomatis can cause?

A
  1. Trachoma
  2. Lymphogranuloma Venereum (LGV)
  3. Reiter’s syndrome (reactive arthritis)
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11
Q

Chronic eye infection and number 1 cause of preventable blindness

A

Trachoma or Trachoma Inclusion Conjunctivitis (TRIC)

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12
Q

Previously the gold standard in Chlamydia spp. before the advent of Molecular techniques and PCR.

A

Cell or Tissue Culture

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13
Q

What are the three (3) tissue/cell culture used in cultivation of Chlamydia spp.?

A
  1. McCoy Cells
  2. HeLa cells
  3. Buffalo Green Monkey
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14
Q

Chlamydia spp. are able to grow in bacterial medium.

a. True
b. False

A

b. False

In order to cultivate Chlamydia/Chlamydophila spp., cell culture (that is also used for viral culture) is required for their growth.

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14
Q

Currently the gold standard for detection of C. trachomatis

A

Nucleic Acid Amplification Test (NAAT)

15
Q

Respiratory pathogens

A
  1. C. pneumoniae
  2. C. psittaci
16
Q

What is C. pneumoniae previously known as?

A

Taiwan Acute Respiratory Strain (TWAR Strain)

17
Q

This is an agent of pneumonia

A

C. pneumoniae

18
Q

What is the respiratory disease that C. psittaci cause?

A

Parrot fever/ Ornithosis/ Psittacosis

19
Q

Mode of Transmission of Parrot fever

A

Contact with infected birds and their droppings