Childhood growth Flashcards

1
Q

What is used to document child growth?

A

The “Red Book” is the book that documents child growth.

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2
Q

What is a centile chart?

[axis, based in what]

A

Age (x-axis) against commulative height (y-axis)

o Based on surveys of large groups of children..

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3
Q

25th centile means what?

A

25% of children will be shorter than the 25th centile and 75% will be taller.

o Note – 50% of the population will be shorter than average (50th centile).

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4
Q

Attaining an accurate measurement for centile chart?

A

o Use well-maintained and accurate equipment.
o Position the child appropriately.
o Get rid of interfering items – i.e. shoes off.
o Calculate age and plot correctly on the chart

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5
Q

Centile charts we use are for cumulative height, what is that?

A

The total of all the growth they have done up until now.

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6
Q

Height velocity?

- height velocity in short children

A

 Height velocity – how fast a child is growing in cm/year (many short children grow at a normal speed).

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7
Q

Causes of variations in growth in the population?

A

o Events before birth – i.e. poor foetal growth, LBW, etc.
o Medical issues in childhood – i.e. malnutrition, chronic disease.
o Genetic factors.
o Randomness – presence of multiple genes and the environment.

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8
Q

The fastest phase of growth?

A

Between the ages of 0-2 years old – children move up and down through the centiles around this time but will move to a centile position by about 2-3 years old.

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9
Q

Another phase of fast growth?

A

o There is another phase of fast growth at puberty.

o The skeleton matures as the child grows, the epiphyses fuse at the end of puberty and growth stops.

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10
Q

Monitoring height growth - when are concerns elicited? :

A

Concerns should invoke the use of the red book for at least a year.

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11
Q

How can Timing of puberty impact on height?

A

Late developers can fall behind in height.

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12
Q

Hormonal Control of Growth?

  • most important hormone
  • what stimulates secretion
  • what inhibits it
  • effects of the hormone
A

 GH is the most important hormonal growth factor.
 GH secretion:
o Stimulated by GnRH – pulsatile release mainly overnight.
o Inhibited by SS.
 Effects of GH:
o Some direct effects.
o Secretion of IGF-1 from liver – then directly influences growth

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13
Q

Most common concern of abnormal growth?

A

Most common concern is short stature and very commonly, there is nothing wrong.

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14
Q

Short stature- commonly, there is nothing wrong when is something wrong?

A

If a child grows SLOWER than normal (not at a later state) then there may be something wrong

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15
Q

If a child grows SLOWER than normal (not at a later state) then there may be something wrong - such as?

A

o Poor nutrition.
o Chronic disease.
o Endocrine causes – GH deficiency, TSH/T4 deficiency.
o Genetic disorders affecting bone growth – achondroplasia, Turner’s & Down’s syndrome.
o Psychological distress and neglect.

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16
Q

 Tall stature – not normally a concern but a few causes?

A

o Syndromes of overgrowth – e.g. Marfan’s syndrome, Soto syndrome.
o GH excess from pituitary tumour.
o Precocious puberty – early puberty but they can also be short as adults as puberty stops earlier.

17
Q

FAT definitionS in adults?

A

o Adults – BMI of >25kg/m2 is overweight, >30kg/m2 is obese.

18
Q

HOW IS obesity defined in children?

A

o Children – BMI centile position – children have a lower BMI than adults that changes with age.

19
Q

Complications of obesity:

A

T2DM

CVD

20
Q

Why people get obese?

A

o Intake vs. expenditure.
o Very few people have deficiencies in leptin.
o There are some gene variants (i.e. in FTO gene) that affects behaviour and appetite.