Chi square and Hardy-Weinberg Flashcards
Mendels assumptions for hybrid cross ratios
-Each allele is dominant or recessive
-Segregation is unimpeded
-Independant assortment occurs
-Fertilisation is random
Reject null hypthesis
Data does not fit mendelian ratios
Fail to reject null hypthesis
Data fits mendelian ratios
Limit chance deviation
Increase sample size
Genotype causes
Different allele combinations
How to work out population genetics
Calculate allele frequencies and genotype frequencies in gene pool
what is pop genetics used for
Determine degree of genetic variation, genotyp distribution and genetic divergence
Microevolution
Changes in allele frequency in a population that does not lead to the formation of a new species
HArdy-weinberg law
Describes what happens to genotype and allele frequencies in an infinetly large, randomly mating pop that is not subject to evolutionary forces such as mutation, migration or selection
Main rule HW
Frequencies of alleles remain constant from one generation to te next
HW assumptions
-Individuals of all genotypes have equal rates of survival and reproduction success (no selection)
-No new alleles are created or converted from one allele into another by mutation
-Individuals do not migrate into or out of the pop
-The pop is infinitely large which results in sampling errors and other random effects being negligible
-Individuals in the pop mate randomly
Consequences of HW
-Dominant traits do not necessarily increase over generations
-Genetic variability can be maintained in a pop since allele frequencies remain unchanged
-Knowing frequency of one genotype allows you to calculate all other genotypes at that locus