Chemotherapy and Immunotherapy

Question 1

What are Akylating agents?

Answer 1

Busulfan (leukaemia)-lung toxicities

Temozolomide (Gliomas)

Question 2

What are the Cisplatin and it’s analogues?

Answer 2

Cisplatin (lung cancer) Nausea and vomiting
Carboplatin (lung and ovarian) Less kidney toxicity
Oxaliplatin (colorectal) Myelosuppression

Question 3

What are the Anti-metabolites?

Answer 3

Methotrexate Myelosuppression

Permetrexed GIT

Question 4

What are the Topoisomerase agents?

Answer 4

Camptothecins (colorectal, SCLC and NSCLC) Myelosuppression

Question 5

What are Anti-microtubule agents?

Answer 5

Taxanes (breast cancer) Neuropathy

Question 6

What are the hormonal treatment for breast cancer?

Answer 6

Tamoxifen
Letrazole
Arimidex
Zoledex

Question 7

What are the hormonal treatment for prostate cancer

Answer 7

Zoledex

Lucrin