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Chemotherapy Flashcards

1
Q

Short Acting Sulfonamide

A

Sulfadiazine

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2
Q

Intermediate Acting Sulfonamide

A

Sulfamethoxazole

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3
Q

Long Acting Sulfonamide

A

Sulfadoxine
Sulfamethopyrazine

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4
Q

Special purpose Sulfonamide

A

Sulfacetamide sodium
Sulfasalazine
Silver sulfasalizine
Mafenide

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5
Q

Adverse Effects of Sulfonamide

A
  1. Renal Irritation, hematuria, albuminiuria and crystalluria
  2. Allergic reactions
  3. Anorexia, nausea
  4. Hemolytic anemia
  5. Kernicterus
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6
Q

Uses of Sulfonamide

A

CUT Masti UNTIL Top Score is Reached
Chanchroid
UTI
Toxoplasmosis
Malaria
Ulcerative colitis
Nocardiosis
Trachoma
Inclusion conjunctivitis
Lymphogranuloma venerum
Topical
Streptococcus pharyngitis
Rheumatoid arthritis

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7
Q

Uses of Cotrimoxazole

A

CTRM Murders Bacterial Pathogens in Urinary Tract
Chanchroid
Thyroid
Resp tract inf
Melioidosis
Bacterial gastroenteritis
Pneumocystis jiroveci inf
Urinary tract inf

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8
Q

Non fluorinated quinolone

A

Nalidixic Acid

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9
Q

Fluoroquinolones - First gen

A

Norfloxacin
Ciprofloxacin
Ofloxacin
Perfloxain

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10
Q

Flouroquinolones - Second Gen

A

Levofloxacin
Moxifloxacin
Gemifloxacin
Prulifloxacin
Lomefloxacin
Sparfloxacin

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11
Q

Uses of fluoroquinolones

A

FQ Usually GET RID of Several Bacteria Common To Man

UTI
Gonorrhea
Eye infection
Typhoid
Resp sys inf
Intra abdominal inf
Diarrhea
Septicemia
Bacterial prostatitis
Chanchroid
Tuberculosis
Meningococcal carrier state
Anthrax
Neutropenia pts

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12
Q

Adverse Effects of fluoroquinolones

A

Nausea, vomiting, abdominal discomfort, diarrhea, skin rashes
Tendonitis
CNS effects - headache, dizziness, insomnia
QTc prolongation

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13
Q

Natural Penicillin

A

Benzyl Penicillin
(Penicillin G)

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14
Q

Semisynthetic Penicillin
Acid resistant alternative

A

Phenoxymethyl Penicillin

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15
Q

Semisynthetic Penicillin
Penicillin Resistant Penicillin

A

Methicillin
Cloxacillin
Dicloxacillin

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16
Q

Semisynthetic Penicillin
Extended Spectrum Penicillin
Amino Penicillins

A

Ampicillin
Bacampicilin
Amoxicilin

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17
Q

Semisynthetic Penicillin
Extended Spectrum Penicillin
Carboxy Penicillins

A

Carbenicillin
Ticarcillin

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18
Q

Semisynthetic Penicillin
Extended Spectrum Penicillin
Ureido Penicillins

A

Piperacillin
Mezlocillin

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19
Q

Beta Lactamase Inhibitors

A

Clavulanic acid
Sulbactam
Tazobactam

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20
Q

Repository Penicillins

A

Procain Penicillin
Benzathine Penicillin

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21
Q

Adverse Effects of Penicillins

A

Hypersensitivity - skin rashes, urticaria, pruritis, fever etc
Local - Pain at site of injection
Jarisch Herxheimer rxn

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22
Q

Uses of Penicillin G

A

PADMA STOPS Syphilis

Pneumococcal
Anaerobic
Diphtheria
Meningococcal
Actinomycosis
Staphylococcal
Tetanus
Others
Prophylactic
Streptococcal
Syphilis

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23
Q

Uses of Ampicillin

A

R U Mad To Say Bye Bye to ampicillin

Respiratory tract inf
UTI
Meningitis
Typhoid
Septicemia
Bacillary dysentery
Bacterial endocarditis

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24
Q

Cephalosporins
First Generation
Oral

A

Cephalexin
Cefadroxil

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25
Q

Cephalosporins
First Generation
Parenteral

A

Cefazolin

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26
Q

Cephalosporins
Second Generation
Oral

A

Cefaclor
Cefuroxime axetil
Cefprozil

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27
Q

Cephalosporins
Second Generation
Parenteral

A

Cefuroxime
Cefoxitin

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28
Q

Cephalosporins
Third Generation
Oral

A

Cefixime
Cefpodoxime proxetil
Cefdinir
Ceftibuten
Ceftamet pivoxil

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29
Q

Cephalosporins
Third Generation
Parenteral

A

Cefotaxime
Ceftriaxone
Ceftizoxime
Ceftazidime
Cefoperazone

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30
Q

Cephalosporins
Fourth Generation
Parenteral

A

Cefepime
Cefpirome

31
Q

Cephalosporins
Fifth Generation
Parenteral

A

Ceftaroline fosamil
Ceftobiprole medocaril

32
Q

Adverse Reactions of Cephalosporins

A

Cephalosporins Have Benn Doing Well Day and Night in patients

Hypersensitivity
Bleeding
Diarrhea
WBC low count
Disulfiram like Reactions
Nephrotoxicity
Pain at injection site

33
Q

Carbapenems

A

Imipenem
Meropenem
Ertapenem
Doripenem
Faropenem

34
Q

Monobactem

35
Q

Short Acting Tetracyclines

A

Chlortetracycline
Tetracycline
Oxytetracycline

36
Q

Intermediate Acting Tetracycline

A

Demeclocycline
Methacycline

37
Q

Long Acting Tetracycline

A

Doxycycline
Minocycline

38
Q

Glycylcycline Tetracycline

A

Tigecycline

39
Q

Adverse Effects of Tetracycline

A

SHARP CT Light

Suprainfection
Hepatotoxicity
Antianabolic effect
Renal toxicity - Fanconi’s Syndrome
Phototoxicity
Pseudotumour cerebri
Teratogenicity
Long term use - leukocytosis
Diabetes insipidus
GIT - nausea vomiting
Hypersensitivity reactions
Thrombophlebitis

40
Q

Adverse Effects of Chloramphenicol

A

GI disturbances - nausea, vomiting, Diarrhea
Bone marrow depression
Gray baby syndrome
Superinfection

41
Q

Aminoglycosides - Systemic

A

Gentamicin
Tobramicin
Sisomicin
Streptomycin
Amikarcin

42
Q

Aminoglycosides - topical

A

Neomycin
Framycetin

43
Q

Adverse Effects of aminoglycosides

A

Ototoxicity
Nephrotoxicity
Neuromuscular blockade

44
Q

Uses of aminoglycosides

A

Gram -ve infections
Bacterial endocarditis
Tuberculosis - streptomycin
Plaque
Tularemia
Brucellosis
Atypical mycobacteria
Gut sterilization- neomycin
Hepatic coma - neomycin
Topical - burns and wounds

45
Q

Macrolide Antibiotics

A

Erythromycin
Roxithromycin
Clarithromycin
Azithromycin
Spiramycin

46
Q

Lincosamide Antibiotics

A

Clindamycin
Lincomycin

47
Q

Aminocyclitol Antibiotic

A

Spectinomycin

48
Q

Glycopeptide antibiotics

A

Vancomycin
Teicoplanin

49
Q

Oxazolidinones

A

Linezolid
Tedizolid

50
Q

Lipopeptide antibiotic

A

Daptomycin

51
Q

Urinary Antiseptics

A

Nitrofurantoin
Methenamine mandelate/ Hexamine
Nalidixic acid

52
Q

Antitubercular First Line Drugs

A

Isoniazid
Rifampicin
Pyrazinamide
Ethambutol
Streptomycin

53
Q

Antitubercular Second line - Fluoroquinolones

A

Ofloxacin
Levofloxacin
Moxifloxacin
Ciprofloxacin

54
Q

Antitubercular Second Line Oral Drugs

A

Ethionamide
Prothionamide
Cycloserine
Terizidone
Paraamino salicylic acid
Rifabutin
Rifapentine

55
Q

Antitubercular Second Line Injectable Drugs

A

Kanamycin
Amikacin
Capreomycin

56
Q

Antileprotic Drugs

A

Dapsone
Clofazimine
Rifampicin
Ethinamide
Ofloxcin
Moxifloxacin
Minocycline
Clarithromycin

57
Q

Polyene antibiotics

A

Amphotericin B
Nystatin
Hamycin
Natamycin

58
Q

Imidazoles

A

Clortrimazole
Econazole
Miconazole
Ketoconazole
Butaconazole
Oxiconazole
Sulconazole
Sertaconazole
Isoconazole

59
Q

Triazoles

A

Fluconazole
Itraconazole
Terconazole
Voriconazole
Posaconazole
Ravuconazole
Isavuconazole

60
Q

Allylamines

A

Terbinafine
Naftifine

61
Q

Drugs acting on cell wall - Pneumocandins/echinocandins

A

Caspofungin
Micafungin
Anidulafungin

62
Q

Drugs acting on nucleus

A

Griseofulvin
Flucytosine

63
Q

Other topical agents

A

Tolnaftate
Undecylenic acid
Benzoic acid
Salicylic acid
Naftifine
Selenium sulfide

64
Q

Anti herpes viral drugs

A

Idoxuridine
Trifluridine
Acyclovir
Valacyclovir
Famciclovir
Ganciclovir
Valganciclovir
Cidofovir
Foscarnet

65
Q

Anti influenza viral drugs

A

Amantadine
Rimantadine
Oseltamivir
Zanamivir
Peramivir

66
Q

Anti hepatitis B drugs

A

Lamivudine
Entecavir
Adefovir dipivoxil
Tenofovir
Telbivudine

67
Q

Anti hepatitis C drugs

A

Ribavirin
Interferon alpha
Sofosbuvir
Simeprevir
Daclatasvir
Ledipasvir
Velpatasvir

68
Q

NRTIs

A

Zidovudine
Didanosine
Stavudine
Lamivudine
Abacavir
Emtricitabine
Tenofovir

69
Q

NNRTIs

A

Nevirapine
Efavirenz
Delavirdine
Etravirine

70
Q

Protease inhibitors

A

Ritonavir
Atazanavir
Indinavir
Nelfinavir
Lopinavir

71
Q

Entry inhibitor

A

Enfuvirtide

72
Q

CCR 5 receptor inhibitor

73
Q

Integrase inhibitor

A

Raltegravir
Dolutegravir

Pharmacology (3 decks)

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