ChemoMan

Question 1

Chemo Man: N

Answer 1

Nitrosoureas (lomustine, carmustine) cause neurotoxicity

Question 2

Chemo Man: C

Answer 2

Platinum-based (cisplatin, carboplatin) are both nephrotoxic and ototoxic

Question 3

Chemo Man: M

Answer 3

Methotrexate causes mucositis

Question 4

Chemo Man: B

Answer 4

Bleomycin, busulfan, carmustine, and lomustine cause pulmonary fibrosis

Question 5

Chemo Man: D

Answer 5

Doxorubicin and other anthracyclines can be cardiotoxic

Question 6

Chemo Man: Al

Answer 6

Immunotherapy targeting CTLA-4 or PD-1/PD-L1: ipilimumab, atezolizumab, durvalumab, nivolumab, pembrolizumab can all cause autoimmune disorders with widespread effects

Question 7

Chemo Man: IP

Answer 7

Ifosfamide and cyclophosphamide can cause hemorrhagic cystitis

Question 8

Chemo Man: VT

Answer 8

Vinca Alkaloids (vincristine, vinblastine and vinorelbine) and Taxanes (paclitaxel, docetaxel) can cause peripheral neuropathy

Question 9

Chemo Man: BMS

Answer 9

Bone Marrow Suppression is a common toxicity of many chemotherapy agents including: alkylators, anthracyclines, platinum-based compounds (cisplatin), taxanes, topoisomerase I and II inhibitors, antimetabolites and vinca alkaloids (vinblastine and vinorelbine)