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TR - Immunology > Chemokines > Flashcards

Chemokines Flashcards

1
Q

CCL2*

Name?
Receptor?
Function?

A

MCP-1

CCR2

Mixed recruitment and endothelial cell migration

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2
Q

CCL3

Name?
Receptor?
Function?

A

MIP-1a

CCR1, CCR5

Mixed leukocyte recruitment (monocytes)

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3
Q

CCL4

Name?
Receptor?
Function?

A

MIP-1B

CCR5

T cell, dendritic cell, monocyte, and NK recruitment; HIV coreceptor

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4
Q

CCL5

Name?
Receptor?
Function?

A

RANTES

CCR1, CCR3, CCR5

Mixed leukocyte recruitment

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5
Q

CCL11

Name?
Receptor?
Function?

A

Eotaxin

CCR3

Eosinophil, basophil, and TH2 recruitment

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6
Q

CCL17

Name?
Receptor?
Function?

A

TARC

CCR4

T cell recruitment

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7
Q

CCL19*

Name?
Receptor?
Function?

A

MIP-3B

CCR7

T cell and dendritic cell migration into parafollicular zones of lymph nodes

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8
Q

CCL20

Name?
Receptor?
Function?

A

MIP-3a

CCR6

Th17 recruitment, DC positioning in tissue

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9
Q

CCL21*

Name?
Receptor?
Function?

A

SLC

CCR7

T cell and dendritic cell migration into parafollicular zones of lymph nodes

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10
Q

CCL22

Name?
Receptor?
Function?

A

MDC

CCR4

NK cell, T cell recruitment

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11
Q

CXCL1

Name?
Receptor?
Function?

A

GROa

CXCR2

Neutrophil recruitment

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12
Q

CXCL5

Name?
Receptor?
Function?

A

ENA-78

CXCR2

Neutrophil recruitment

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13
Q

CXCL8*

Name?
Receptor?
Function?

A

IL-8

CXCR1, CXCR-2

Neutrophil recruitment

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14
Q

CXCL10*

Name?
Receptor?
Function?

A

IP-10

CXCR3, CXCR3B

Effector T cell recruitment

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15
Q

CXCL11

Name?
Receptor?
Function?

A

I-TAC

CXCR3, CXCR7

Effector T cell recruitment

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16
Q

CXCL12*

Name?
Receptor?
Function?

A

SDF-1aB

CXCR4

Homing naive B cells to LNs

17
Q

CXCL13*

Name?
Receptor?
Function?

A

BCA-1

CXCR5

B cell migration into follicles; T follicular helper cell migration into follicles

18
Q

CXCL14

Name?
Receptor?
Function?

A

BRAK

No receptor

Monocyte and dendritic cell migration

19
Q

XCL1

Name?
Receptor?
Function?

A

Lymphotactin

XCR1

T cell and NK cell recruitment

20
Q

CX3CL1

Name?
Receptor?
Function?

A

Fractalkine

CX3CR1

T cell, NK cell, and monocyte recruitment; CTL and NK cell activation

21
Q

CCL1

Name?
Receptor?
Function?

A

I-309

CCR8

Monocytes recruitment and endothelial cell migration

TR - Immunology (2 decks)

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