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Immunology > Chemokines > Flashcards

Chemokines Flashcards

1
Q

####*#

Chemokine: CCL2
ON?
CR?
MF?

A

MCP-1

CCR2

Mixed leukocyte recruitment

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2
Q

Chemokine: CCL3
ON?
CR?
MF?

A

MIP-1 ALPHA

CCR1, CCR5

Mixed leukocyte recruitment

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3
Q

Chemokine: CCL4
ON?
CR?
MF?

A

MIP-1 BETA

CCR5

T cell, dendritic cell, monocyte, and NK recruitment; HIV coreceptor

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4
Q

Chemokine: CCL5
ON?
CR
MF

A

RANTES

CCR1, CCR3, CCR5

Mixed leukocyte recruitment

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5
Q

Chemokine: CCL11
ON
CR
MF

A

Eotaxin

CCR3

Eosinophil, basophils, and T Helper 2 recruitment

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6
Q

Chemokine: CCL17
ON
CR
MF

A

TARC

CCR4

T cell recruitment

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7
Q

##*#

Chemokine: CCL19
ON
CR
MF

A

MIP-3 BETA

CCR7

T cell and dendritic cell migration into parafollicular zones of lymph nodes

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8
Q

Chemokine: CCL20
ON
CR
MF

A

MIP-3 ALPHA

CCR6

Th17 recruitment, DC positioning in tissue

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9
Q

####

Chemokine: CCL21
ON
CR
MF

A

SLC

CCR7

T cell and dendritic cell migration into parafollicular zones of lymph nodes

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10
Q

Chemokine: CCL22
ON
CR
MF

A

MDC

CCR4

NK cell, T cell recruitment

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11
Q

Chemokine: CXCL1
ON
CR
MF

A

GRO ALPHA

CXCR2

Neutrophil recruitment

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12
Q

Chemokine: CXCL5
ON
CR
MF

A

ENA-78

CXCR2

Neutrophil recruitment

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13
Q

###

Chemokine: CXCL8
ON
CR
MF

A

IL-8

CXCR1, CXCR2

Neutrophil recruitment

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14
Q

####

Chemokine: CXCL10
ON
CR
MF

A

IP-10

CXCR3, CXCR38

Effector T cell recruitment

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15
Q

Chemokine: CXCL11
ON
CR
MF

A

I-TAC

CXCR3, CXCR7

Effector T cell recruitment

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16
Q

###

Chemokine: CXCL12
ON
CR
MF

A

SDF-1 ALPHA BETA

CXCR4

Mixed leukocyte recruitment; HIV coreceptor

17
Q

####

Chemokine: CXCL13
ON
CR
MF

A

BCA-1

CXCR5

B cell migration into follicles; T follicular helper cell migration into follicles

18
Q

Chemokine: CXCL14
ON
CR
MF

A

BRAK

No receptor given

Monocyte and dendritic cell migration

19
Q

Chemokine: XCL1
ON
CR
MF

A

Lymphotactin

XCR1

T cell and NK cell recruitment

20
Q

Chemokine: CX3CL1
ON
CR
MF

A

Fractalkine

CX3CR1

T cell, NK cell, and monocyte recruitment; CTL and NK cell activation

21
Q

Chemokine: CCL1
Original Name?
Chemokine Receptor?
Major Function?

A

I-309

CCR8

Monocyte recruitment and endothelial cell migration

Immunology (4 decks)

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