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Errthing > chemo > Flashcards

chemo Flashcards

1
Q

MOA: 5-FU

A

pyrimidine analogue

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2
Q

MOA: alemtuzumab

A

targets CD52

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3
Q

MOA: axitinib

A

TKI

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4
Q

MOA: azathioprine

A

purine analogue

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5
Q

MOA: bevacizumab

A

VEGF-A inhibitor

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6
Q

MOA: bleomycin

A

binds DNA (causing strand breaks? - exact action unknown)

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7
Q

MOA: bortezomib

A

protease inhibitor

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8
Q

MOA: brentuximab

A

targets CD30

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9
Q

MOA: busulfan

A

alkylating agent

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10
Q

MOA: capecitabine

A

prodrug for 5-FU (pyrimidine analogue)

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11
Q

MOA: cabazitaxel

A

taxane (microtubule stabilizer)

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12
Q

MOA: carboplatin

A

cross-links DNA

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13
Q

MOA: carmustine

A

alkylating agent (notrosourea)

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14
Q

MOA: cetuximab

A

EGFR inhibitor

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15
Q

MOA: cisplatin

A

cross-links DNA

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16
Q

MOA: cobimetinib

A

MEK inhibitor

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17
Q

MOA: crizotinib

A

inhibits ALK and ROS1

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18
Q

MOA: cyclophosphamide

A

alkylating agent (nitrogen mustard)

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19
Q

MOA: cytrarabine / ara-c

A

pyrimidine analogue

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20
Q

MOA: dabrafenib

A

BRAF inhibitor

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21
Q

MOA: dacarbazine

A

alkylating agent

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22
Q

MOA: dasatinib

A

Bcr-Abl TKI

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23
Q

MOA: docetaxel

A

taxane (microtubule stabilizer)

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24
Q

MOA: doxorubicin

A

DNA intercalation

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25
MOA: epirubicin
DNA intercalation
26
MOA: erlotinib
EGFR inhibitor
27
MOA: etanercept
inhibits TNF-alpha
28
MOA: etoposide
topoisomerase inhibitor
29
MOA: everolimus
mTOR inhibitor
30
MOA: fludarabine
purine analogue
31
MOA: gefitinib
EGFR inhibitor
32
MOA: gemcitabine
pyrimidine analogue
33
MOA: idelalisib
PI3K inhibitor
34
MOA: ifosfamide
alkylating agent (nitrogen mustard)
35
MOA: imatinib
Bcr-Abl TKI
36
MOA: infliximab
inhibits TNF-alpha
37
MOA: ipilimumab
targets CTLA-4
38
MOA: irinotecan
topoisomerase inhibitor
39
MOA: lenalidomide
derivative of thalidomide, mechanism unknown
40
MOA: leucovorin / folinic acid
inhibits thymidylate synthase
41
MOA: lomustine
alkylating agent (notrosourea)
42
MOA: melphalan
alkylating agent (nitrogen mustard)
43
MOA: mercaptopurine
purine analogue
44
MOA: methotrexate
inhibits dihydrofolate reductase
45
MOA: mitomycin
cross-links DNA
46
MOA: nivolumab
PD1 inhibitor
47
MOA: oxaliplatin
cross-links DNA
48
MOA: paclitaxel
taxane (microtubule stabilizer)
49
MOA: panitumumab
EGFR inhibitor
50
MOA: pazopanib
multikinase TKI
51
MOA: pembrolizumab
PD1 inhibitor
52
MOA: pemetrexed
inhibits thymidylate synthase and dihydrofolate reductase
53
MOA: pertuzumab
targets HER2
54
MOA: rituximab
targets CD20
55
MOA: sirolimus
mTOR inhibitor
56
MOA: sorafenib
multikinase TKI
57
MOA: sunitinib
multikinase TKI
58
MOA: tacrolimus
calcineurin inhibitor
59
MOA: temozolomide
alkylating agent
60
MOA: temsirolimus
mTOR inhibitor
61
MOA: topotecan
topoisomerase inhibitor
62
MOA: trametinib
MEK inhibitor
63
MOA: trastuzumab
targets HER2
64
MOA: vemurafenib
BRAF inhibitor
65
MOA: vinblastine
disrupts microtubules (vinca alkaloid)
66
MOA: vincristine
disrupts microtubules (vinca alkaloid)

Errthing (12 decks)

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