Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hem/Onc > Chemo > Flashcards

Chemo Flashcards

1
Q

Name the M-Phase Drugs

A

Vincristine, Vinblastine, Taxols

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name the G2-Phase Drugs

A

Etoposide, Bleomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Key side effect of anthracyclines?***

A

Cardiotoxicity–>CHF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

SE of asparaginase

A

Pancreatitis, coagulopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SE of Bleomycin

A

Pulmonary Fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

SE of Cisplatin***

A

N/V, Ototoxicity, Nephrotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

SE of Cyclophosphamide/ ifosfamide***

A

hemorrhagic cystitis

Secondary AML: long interval (c5, c7 abnormalities)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

SE of cytosine arabinoside (Ara C)

A

cerebellar toxicity, hemorrhagic conjunctivitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

SE of dactinomycin

A

hepatic vaso-occlusive disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

SE of Etoposide

A 
anaphylaxis
Secondary AML (short interval, 11q23)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which two chemo agents can cause secondary AML? What is the difference?***

A

1) Etoposide: short interval, c11q23

2) Cyclophosphamide/ifosfamide: long interval, c5, c7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

SE of irinotecan

A

Severe diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

SE of nitrosoureas

A

delayed myelosuppression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

SE of rituximab

A

HepB reactivation, PML

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SE of Taxols

A

Peripheral neuropathy, HSR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

SE of vincristine

A

neuropathy

17
Q

Antidote for methotrexate ***

A

Folinic acid (Leucovorin)

18
Q

Antidote for 5-FU

A

Thymidine

19
Q

Toxicity modifier for cyclophosphamide/ifosfamide ***

A

MESNA (required with ifosfamide)

20
Q

Toxicity modifier for anthracyclines ***

A

dexrazoxane

21
Q

Toxicity modifier for cytosine arabinoside

A

dexamethasone eye drops

22
Q

Toxicity modifier for taxols

A

H1 and H2 blockers

23
Q

Toxicity modifier for irinotecan

A

cefpodoxine preRx, atropine, imodium

24
Q

Which four agents are prodrugs?

A

Cyclophosphamide, Ifosfamide, Temozolamide, Irinotecan

Hem/Onc (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions