chemo

Question 1

Cisplatin

Answer 1

Platinol
alkylating agent
Amiofostine to prevent nephrotoxicity
IV fluid and mannitol

Question 2

oxaliplatin

Answer 2

Eloxatin
alkylating agent
+ leucovorin + 5FU for colorectal cancer

Question 3

carboplatin

Answer 3

Paraplatin
alkylating agent
analog of Cisplatin-less nephrotoxic

Question 4

Amiofostine

Answer 4

Ethyol

SE: severe hypotension. D/c all HTN med 2 hrs b4.

Question 5

Busulfan

Answer 5

Myleran
alkylating agent
-add allopurinol
cause pulmonary fibrosis and skin hyperpigmentation

Question 6

cyclophosphamide

Answer 6

Cytoxan
alkylating agent; hemorrhagic cystitis (acrolein); alopecia
MESNA and hydration

Question 7

Ifosfamide

Answer 7

Ifex

alkylating agent; MESNA and hydration

Question 8

Carmustine

Answer 8

BiCNU
alkylating agent; pulmonary fibrosis, liver/renal toxic, BMS
for brain tumor

Question 9

Lomustine

Answer 9

CeeNu
alkylating agent; pulmonary fibrosis, liver/renal toxic, BMS
for brain tumor

Question 10

stretozocin

Answer 10

Zanocar
alkylating agent; pancreatis cancer
cause DM, extravasation, and nephrotoxic.

Question 11

Melphalan

Answer 11

Alkeran

alkylating agent; fertility

Question 12

Mechlorethamine

Answer 12

Mustargen
Extravastation; tx with Na thiosulfate
fertility
Valchlor-gel-refrigerated

Question 13

Altretamine

Answer 13

Hexalen
alkylating agent; ovarian cancer
fertility; peripheral neuropathy

Question 14

Procarbazine

Answer 14

Matulane
alkylating agent
kids: tremor, convulsion, coma
hypetensive ciris with tyramine food, MOAI
alcohol-- disulfiram rxn

Question 15

Bendamustine

Answer 15

Treanda
alkylating agent;
3h RT; 24 hr refrigerated; protect fr light
myelosuppression, infusion rxn; anaphylaxis, tumor lysis syndrome (use allopurinol)