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Chemical Pathology Rotations > Chemical Pathology Day 3 > Flashcards

Chemical Pathology Day 3 Flashcards

1
Q

What are the two groups of hormones tested for here at KATH

A

Thyroid hormones
Fertility hormones

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2
Q

What are the hormonal constituents of the thyroid function test

A

TSH
Tri-iodothyronine
Thyroxine

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3
Q

What is the interpretation for a raised T3, raised T4 and low TSH

A

Hyperthyroidism

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4
Q

What is the interpretation for a raised T3, low T4 and low TSH

A

T3 thyrotoxicosis

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5
Q

What is the interpretation for a normal T3, raised T4 and low TSH

A

Thyrotoxicosis

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6
Q

What is the interpretation for a decreased T3, decreased T4 and raised TSH

A

Hypothyroidism

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7
Q

Why should hormone samples be taken in the morning

A

Concept of circadian rhythm

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8
Q

What tube is used for hormonal assays

A

Gel separator tube

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9
Q

Fasting is not required for hormonal testing
True or false

A

True

With the exception of prolactin

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10
Q

What are the constituents of a fertility test

A

LH
FSH
Prolactin
Progesterone
Testosterone
Estrogen

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11
Q

Which of the fertility tests require a fasting sample

A

Prolactin

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12
Q

What new chemical hormone is being added to the fertility tests

A

Anti-Mullerian hormone (to test for egg production)

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13
Q

At what day does progesterone peak at the menstrual cycle

A

21st day

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14
Q

What does the material and test section on a lab form mean

A

What material or sample do you need for the test

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15
Q

What are some information to be provided on the lab form

A

Surname
Other names
(Lead) clinician
Clinical summary and diagnosis
Material and test
Date of request
Signature of the doctor
Time sample taken
Time specimen received

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16
Q

What are some factors that can affect the interpretation of fertility hormone results

A

Sex of the patient
Age of the patient
Diet
Time of sampling
Stress and anxiety
Posture of the patient (should be standardized if possible. Point posture from lying to standing, there may be an increase of as much as 13% in the concentration of serum proteins due to redistribution of fluid in the extracellular space)
Effect of exercise (some analytes are affected by muscular activity Eg. CK-MB, etc)
Pregnancy (there are changes in body chemicals during pregnancy)
Menstrual cycle
Drug history
Analytical factors (was there any problem during the process of obtaining the results - machine calibration, quality checks)
Artefactual factors
Physical size (creatinine levels)
Hereditary factor (Eg. Sickle cell)

17
Q

What is the value of the adult total bilirubin up to

A

3 - 22 umol/l

18
Q

What is the upper limit for total bilirubin for pre-mature babies

A

205.2 umol/l

19
Q

What is the upper limit for total bilirubin for full-term babies (9-months babies)

A

171 umol/l

20
Q

Which specific time should hormone samples be taken

A

Before 10 am

Chemical Pathology Rotations (5 decks)

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