Chemical Buffers- 1st Line Of Defense

Question 0

Phosphate buffer

Answer 0

Important in kidney and icf
Buffer= mix of h2po4- and hpo42-
PK=6.8

H3po4- H+ + h2po4- H+ +hpo42-

Question 1

Bicarbonate system

Answer 1

-carbonic acid and na bicarbonate pK=6.1

Co2 + h2o -> h2co3 -> h+ + hco3-

Urine pH buffer (5-7)
Major ecf buffer

Question 2

Proteins

Answer 2

Largest amount, most powerful
-high concentration 
PK near 7.4
-buffers acids and bases
-important in icf and ecf