Chapters 1-3 Flashcards
T/F: CNS axons regenerate if cut
F
T/F: PNS myelinated neurons can regenerate if cut
T (go down endoneurial sheath formed by Schwann scells)
Rx for Guillain-Barré syndrome
Plasmaphoresis; gamma globulin
Dorsal rami innervate ____ (3)
Skin of medial 2/3 of back from vertex of skull ; deep intrinsic muscles; facet joints between vertebrae
Alternate name for the suboccipital nerve
Dorsal ramus of C1
Alternate name for the dorsal ramus of C2
Greater occipital nerve
The 4 cranial nerves that are mixed are derived from. . .
Pharyngeal arches
Which CN are derived from pharyngeal arches?
V, VII, IX, X
What is the only saddle joint?
Carpometacarpal joint of thumb between trapezium/base of first metacarpal
T/F: There are no white rami above/below T1 and L2/3 levels
T
T/F: Postganglionic sympathetic fibers in the grey rami rejoin spinal nerves at all levels
T
Sympathetic fibers leave in __ rami to enter paravertebral trunk
White
Eccrine sweat glands and erectile tissues are triggered by ___
Ach (SNS)
Physiologic sensations other than pain travel with sensory fibers nearby to ___
Parasympathetic axons in vagus or pelvic splanchnic nerves
Baroreceptors in the arteries controlled by ___
PNS
Chemoreceptors in the stomach, arteries controlled by ___
PNS
Visceral pain fibers accompany ___ nerves
Sympathetic nerves back to CNS
Most visceral pain is referred to ___ dermatomes
T1 to L2
Horner’s syndrome triad
Ptosis, miosis, anhydrosis
Pathophysiology of Shy Drager Syndrome
Degeneration of preganglionic sympathetic/parasympathetic neurons in brainstem & spinal cord, degeneration of neurons in most ganglia
Sx of Shy Drager Syndrome
Impotence, urine retention, dizziness on standing, blurred vision, inability to sweat
Reflexes include at minimum ___ and ____
1 sensory neuron and 1 motor neuron linked at synapse
Describe muscle stretch reflex
Muscle spindles in skeletal muscle stimulated by stretch –> reflex contraction
Describe autonomic reflex
Sensory stimuli cause reflex contraction of smooth muscle/secretion of gland/change in rate or force of contraction of heart
Arteries that lack collateral circulation
Central artery of retina and interlobular arteries of kidney
Pathophysiology of Raynaud’s
Hyperconstriction of arteriovenous shunts in fingers/toes
Where does lymph enter the venous system?
Junction of IJV and subclavian vein at neck by way of right lymphatic duct (R) and thoracic duct (L)
Vertebral arch consists of ____
2 pedicles and 2 laminae that form a spinous process
Spina bifida is a failure of ___
laminae to fuse to form spinal process
Kyphosis
Abnormal increase in posterior curvature of the spine
Lordosis
Abnormal increase in anterior curvature of the spine
Scoliosis
Abnormal increase in lateral curvature of spine
Zygapophyseal (facet) joints
Between superior and inferior processes at junction of each pedicle and lamina
Zygapophyseal (facet) joints permit ___ motion
Gliding
Disc components
Fibrocartilaginous annulus fibrosus surrounding semigelatinous nucleus pulposus
Anterior longitudinal ligaments
Covers anterior and lateral parts of vertebrae; limits extension
Posterior longitudinal ligaments
Covers posterior parts of vertebrae; limits flexion; weaker than anterior counterpart
Ligamentum flavum
Extends between laminae of adjacent vertebrae; limits flexion
Intervertebral foramina
Transmit dorsal and ventral roots of spinal nerves; bounded by pedicles/facets/bodies
Dura mater ends at ___ level
S2
Arachnoid mater extends to ___ level
S2
____ space contains CSF and has a normal pressure of approximately ____ mm H2O
Subarachnoid; 100
Denticulate ligaments
Lateral extension of pia that anchor spinal cord to dura
Filum terminale
Pia extending from L2 to S2
First 7 cervical nerves exit ___ to cervical vertebrae with same #
superior
Most nerves exist ___ to vertebrae of same #
inferior (below T1)
Cauda equina
Dorsal and ventral roots of lumbar/sacral spinal nerves extending inferior at L2 vertebra
Lumbar puncture sampled between ___
L4 and l5
Normal LP will puncture ___ ligaments
Supraspinous and interspinous
Midline LP will puncture ____
Ligamentum flavum
Radiculopathy
Compression of roots of spinal nerve resulting in pain and paresthesias along dermatomes supplied by compressed sensory roots
Spondylitis
Additional bone growth by osteophytes at margins of vertebral bodies; ALL and sacroiliac joints may become calcified (“bamboo spine”, ankylosis)
Spondylosis
Degenerative changes in intervertebral disks
Herniated disc
NP protrudes at posterolateral part of annulus fibrosis; compresses roots of lower cervical or lower lumbar spinal nerves; most common at C6/C7