Chapter 9 Protein Regulation Part II Flashcards
What is the function of amino acids besides being the building blocks for peptides and proteins?
Amino acids may be oxidized for fuel.
What is the cofactor we will explore in this chapter?
The pyridoxal phosphate.
From what vitamin is the cofactor pyridoxal pyrophosphate derived?
Vitamin B6. Vitamin B6 is converted to the aldehyde and phosphorylated to form the cofactor pyridoxal pyrophosphate.
How is the cofactor attached to the enzymes that require this cofactor?
Schiff base.
Ammonotelic
excess ammonia directly flushed into the surrounding water.
Ureotelic
organisms that convert ammonia to urea.
Uricotelic
organisms that convert ammonia to uric acid.
Why do we make urea?
ammonia within the body must be eliminated.
What is the source of the nitrogen in urea biosynthesis?
amino acids.
What are the central four amino acids of nitrogen metabolism?
glutamate
glutamine
alanine
aspartate
What molecule forms when amino group is freed from glutamate?
alpha-ketoglutarate
What molecule forms when amino group is freed from glutamine?
alpha-ketoglutarate
What molecule forms when amino group is freed from alanine?
pyruvate
What molecule forms when amino group is freed from aspartate?
oxaloacetate
In what organ does amino acid catabolism take place?
Liver