Chapter 9 - Erythrocyte Metabolism and Membrane Structure and Function

Question 1

Which RBC process does not require energy?

Answer 1

a. Oxygen transport

Question 2

What pathway anaerobically generates energy in the form of ATP?

Answer 2

c. Embden-Meyerhof pathway

Question 3

Which is true concerning 2,3-BPG?

Answer 3

b. Enhances O2 release from hemoglobin

Question 4

To survive, the RBC must detoxify peroxides. What hexose-monophosphate shunt product(s) accomplishes detoxification?

Answer 4

d. NADPH and reduced glutathione

Question 5

Which of the following helps maintain RBC shape?

Answer 5

b. Cytoskeletal proteins

Question 6

The glycolipids of the RBC membrane:

Answer 6

b. Carry RBC antigens.

Question 7

RBC membranes block passage of most large molecules such as proteins, but allow passage of small molecules such as the cations Na1, K1, and Ca11. What is the term for this membrane property?

Answer 7

a. Semipermeable

Question 8

RBC membrane phospholipids are arranged:

Answer 8

c. In two layers whose composition is asymmetric.

Question 9

RBC membrane cholesterol is replenished from the:

Answer 9

a. Plasma.

Question 10

The hemoglobin iron ion may become oxidized to the 13 valence state by several pathological mechanisms. What portion of the Embden-Meyerhof pathway reduces iron to the physiologic 12 valence state?

Answer 10

a. Methemoglobin reductase pathway

Question 11

Which of the following is an example of a transmembrane or integral membrane protein?

Answer 11

a. Glycophorin A

Question 12

Abnormalities in the horizontal and vertical linkages of the transmembrane and cytoskeletal RBC membrane proteins may be seen as:

Answer 12

a. Shape changes.