Chapter 7 - Hematopoiesis

Question 1

The process of formation and development of blood cells is
termed:

Answer 1

a. Hematopoiesis

Question 2

During the second trimester of fetal development, the primary site of blood cell production is the:

Answer 2

d. Liver

Question 3

Which one of the following organs is responsible for the maturation of T lymphocytes and regulation of their expression of CD4 and CD8?

Answer 3

c. Thymus

Question 4

The best source of active bone marrow from a 20-year-old would be:

Answer 4

a. Iliac crest

Question 5

Physiologic programmed cell death is termed:

Answer 5

b. Apoptosis

Question 6

Which organ is the site of sequestration of platelets?

Answer 6

c. Spleen

Question 7

Which one of the following morphologic changes occurs during normal blood cell maturation:

Answer 7

c. Condensation of nuclear chromatin

Question 8

Which one of the following cells is a product of the CLP?

Answer 8

b. T lymphocyte

Question 9

What growth factor is produced in the kidneys and is used to treat anemia associated with kidney disease?

Answer 9

a. EPO

Question 10

Which one of the following cytokines is required very early in the differentiation of a hematopoietic stem cell?

Answer 10

d. FLT3 ligand

Question 11

When a patient has severe anemia and the bone marrow is unable to effectively produce red blood cells to meet the increased demand, one of the body’s responses is:

Answer 11

a. Extramedullary hematopoiesis in the liver and spleen

Question 12

Hematopoietic stem cells produce all lineages of blood cells in sufficient quantities over the lifetime of an individual because they:

Answer 12

b. Have the ability of self-renewal by asymmetric division