Chapter 9 Flashcards
Cells maintain their normal metabolic functions by producing and using energy in the form of
Adenosine triphosphate ATP
The most efficient method of generating this needed energy is via
Aerobic metabolism
The sensitivity of cells to the lack of oxygen varies from organ system to organ system. The sensitivity is called ischemic lack of oxygen sensitivity, and its greatest in the
Brain heart and lungs
It may take only 4 to 6 minutes of anaerobic metabolism before one or more of these vital organs are injured beyond repair
Skin and muscle tissue have a significantly longer ischemic sensitivity as long as 4 to 6 hours abdominal organs generally fall between these two groups and are able to survive 45 to 90 minutes of anaerobic metabolism
The correct definition of shock is
A lack of tissue perfusion oxygenation at the cellular level that leads to anaerobic metabolism and loss of energy production needed to support life
When blood is lost from the circulation, the heart is stimulated to increase cardiac output by increasing the strength and rate of contractions. The stimulus results from the release
Epinephrine From the adrenal glands
At the same time the sympathetic nervous system releases nor epinephrine to constrict blood vessels to reduce the size of the container and bring it more into proportion with the volume of remaining fluid
A patient who has signs of compensation such as tachycardia is already in shock not going into shock when the defense mechanisms can no longer compensate for the amount of blood lost a patient’s blood pressure will drop his decrease in blood pressure Marx to switch from
Compensated to D compensated shock a sign of impending death
Class one hemorrhage
A loss of up to 15% of blood volume in the adult of the 750 mL this stage has few clinical manifestations tachycardia is often minimal and no measurable change in blood pressure pulse pressure or ventilatory rate occur most healthy patient sustaining this amount of hemorrhage require only maintenance fluid as long as no further blood loss occurs
Class 2 hemorrhage
A loss of 15% to 30% of blood volume 750 to 1500 ML most adults are capable of compensating for this amount of blood loss by activation of the sympathetic nervous system which will maintain their blood pressure clinical findings include increased dilatory rate tachycardia and narrowed pulse pressure clinical clues to this phase are tachycardia tachypnea and normal systolic blood pressure because the blood pressure is normal this is compensated shock that is the patient is in shock but is able to compensate for the time being
Class 3 hemorrhage
Represents a loss of 30% to 40% of blood volume 1500 to 2000 ML when blood loss reaches this point most patients are no longer able to compensate for the volume loss and hypotension occurs classified as a shock or obvious and include tachycardia heart rate greater than 120 tachypnea then a toy rate of 30 to 40 and severe anxiety and confusion.
Class for hemorrhage
Represents a loss of more than 40% of blood volume greater than 2000 ML the stage of severe shock is characterized by marked tachycardia heart rate greater than 140 to keep near the Letory rate greater than 35 profound confusion or lethargic and greatly decreased systolic blood pressure typically in a range of 60 mmHg
Shark research has demonstrated that for lost blood, the replacement ratio with electrolyte solution should be
3 L of replacement for each liter of blood lost This high ratio of replacement fluid is required because only about 1/4 to 1/3 of the volume of an isotonic crystalloid solution such as normal Celine or lactated ringer’s solution remains in the intravascular space 30 to 60 minutes after infusing it.
The result of administering too much crystalloid is
Increased interstitial fluid Adema which impairs oxygen transfer to the remaining RBCs and into the tissue cells. The goal is not to raise the blood pressure to normal levels but to provide only enough fluid to maintain perfusion and continue to provide oxygenated RBC used to the heart brain and lungs
Best crystalloid solution for treating hemorrhagic shock
Lactated ringer’s solution. Normal Celine is another isotonic crystalloid solution that can be used for volume replacement, but it’s used may produce hyperchloremia ( Marked increase in the blood chloride level, leading to acidosis
Distributive shock or vasogenic shock
Occurs when the vascular container in large is without a proportional increase in fluid volume after trauma this is typically found in patients who have sustained a spinal cord injury