Chapter 8- nutrients involved in energy metabolism Flashcards
Thiamin
vitamin B1; required for metabolism of carbohydrate and branched-chain amino acids; assists in production of DNA, RNA, and neurotransmitters
beriberi
thiamin deficiency; causes muscle wasting and nerve damage
Riboflavin
vitamin B2; water soluble, involved in oxidation-reduction reactions, part of coenzyme glutathione peroxidase, light sensitive
ariboflavinosis
riboflavin deficiency; sore throat, swollen mucous membranes
Niacin
vitamin B3; comes in two forms - nicotinic acid and nicotinamide, required for oxidation-reduction reactions of carbohydrates, proteins, and fats, and can be made from amino acid tryptophan
pellagra
severe niacin deficiency
Pyridoxine
vitamin B6; group of 3 related compounds, coenzyme in amino acid metabolism and gluconeogenesis
B6 toxicity
from high-dose supplements- nerve damage and skin lesions
B6 deficiency
affects skin, blood, and nerve tissues
Folate
works with enzymes critical for DNA synthesis, cell differentiation, amino acid metabolism, and repair of damaged cells, plays a special role in embryo development
folate deficiency
includes neural tude defects in infants, anemia, and heart disease
Cyanocobalamin
vitamin B12; includes a number of compounds that have a cobalt center surrounded by a ring structure; works with coenzymes to assist DNA synthesis and essential for nervous system functioning
pantothenic acid
essential for fatty acid metabolism- required for synthesizing cholesterol, steroids, and detoxification of drugs
biotin
a component of coenzymes used for fatty acid synthesis and gluconeogenesis, contributes to carbohydrate, fat, and protein metabolism
biotin deficiency
mostly seen in large consumption of raw egg whites over time, and in people who must consume food intravenously
choline
vitamin-like substance needed for metabolism, cell membranes, neurotransmission, fat and cholesterol maetabolism and transport, and homocysteine metabolism
choline sources
widespread in foods
choline deficiency
fat accumulation in the liver
choline toxicity
comes from excess supplementation
iodine
component of thyroid hormones; regulates body temperature and metabolism, important for reproduction and growth
iodine sources
saltwater fish, iodized salt, foods prepared with iodized salt
excess iodine
interferes with thyroid function
goiter
enlarged thyroid gland; occurs with iodine toxicity AND deficiency
Iodine deficiency disorders (IDDs)
cretinism- mental retardation and stunted growth; hypothyroidism- low thyroid hormone; decreased body temperature, cold intolerance, weight gain, fatigue, sluggishness
hyperthyroidism
high levels of thyroid hormone caused by Graves’ disease- weight loss, increased heat production, muscular tremors, nervousness, racing heartbeat, protrusion of the eyes
chromium
assists insulin to transport glucose from the bloodstream into cells, important for RNA and DNA metabolism, supports immune function and growth
chromium sources
widespread in foods; supplementation safety unkown
chromium deficiency
inhibits glucose uptake in cells, causing a rise in blood glucose and insulin levels
manganese
cofactor in protein, fat, and carbohydrate metabolism, gluconeogenesis, cholesterol synthesis, and urea formation, part of antioxidant superoxide dismutase
manganese sources
whole grain foods
manganese toxicity
impairs nervous system causing spasms and tremors
sulfur
major mineral, component of thiamin and biotin, part of amino acids methionine and cysteine, required by liver for alcohol detoxification, assists in maintaining acid-base balance
inadequate b-vitamin intake
impacts ability to perform physical activity; diets high in unenriched processed foods provide inadequate levels of b-vitamins
thiamin sources
pork products, sunflower seeds, beans, whole or enriched grains
riboflavin sources
milk, enriched foods, meat
niacin sources
meat, fish, poultry, enriched breads and cereals
vitamin B6 sources
meat, fish, poultry, enriched cereals, starch vegetables
folate sources
green leafy vegetables, bread and grain products, liver, lentils, asparagus, and oatmeal
B12 sources
meat, eggs, dairy, seafood
pantothenic acid sources
chicken, beef, egg yolk, potatoes, oat cereals, tomato products