Chapter 8: Cohort Studies Flashcards

1
Q

List the study design for cohort studies

A

Prospective and retrospective

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2
Q

What is prospective studies?

A

Known as “forward in time”, is when investigator identifies participants, measures, exposure status, and follows the cohort (person in study) over time to monitor outcome events.

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3
Q

What is retrospective studies?

A

Know as “backward in time”, investigator identifies a cohort with already available exposure and outcome data (past data).

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4
Q

Between prospective and retrospective which is expensive and why?

A

Prospective is expensive as the cohort followed over time.

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5
Q

Which cohort studies has less control over selection of participants?

A

Retrospective does becasue they are using already available data.

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6
Q

How are study cohort chosen for cohort studies?

A

They choose if they are at risk of becoming a case.

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7
Q

Who is excluded from cohort studies?

A
  • Individual who already have a disease outcome of interest.
  • Those who are not risk and can’t become a case.
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8
Q

What is an analytic study?

A

Measures the association between exposures and outcomes.

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9
Q

What are the down side of using retrospective studies?

A
  • Infromation outdated
  • Bias
  • Misinformation
  • Lack of data
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10
Q

Can incidence be collected in a cohort study?

A

Yes, since data is being collected in real time.

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11
Q

What is attributable risk?

A

Attributable risk is the amount of disease incidence that can be attributed to a specific exposure.

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12
Q

What is attributable risk percentage?

A

Attributable risk percentage is what proportion of the risk in exposed persons is due to the exposure.

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13
Q

What is population attributable risk?

A

Population attributable risk is what proportion of the disease incidence in a total population (both exp/unexp people) can be attributed to a specific exposure.

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14
Q

What is population attributable percentage?

A

Population attributable risk percentage is the proportion of the incidence in the total population that is attributable to the exposure.

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15
Q

Risk ratio is used for what study

A

Risk ratio is used for cohort studies.

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16
Q

Risk ratio

A

Used to compare the probability (risk) for the outcome across two groups.

17
Q

Rate ratio

A

Used to compare the incidence rates, person-time rates. or mortality rates of two groups.

18
Q

When does the odd ratio approximate the risk ratio?

A

For health-related states or events that are rare affecting less than 10% of the population.

19
Q

What type of bias is in a cohort studies?

A

Selection and information bias.