Chapter 8 Flashcards

1
Q

what is the genetic language

A

nucleic acid

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2
Q

what are the characteristics of genetic material.

A
  1. must contain complex information
  2. must replicate accurately
  3. must encode the phenotype
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3
Q

what is the product of a gene

A

protein

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4
Q

what did mishear find (p)

A

puss

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5
Q

what did kossel find (b)

A
bases
adenine
cytosine
guanine
thymine
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6
Q

what did levee find

A

found nucleotides.

  1. sugar
  2. phosphate
  3. base
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7
Q

Chargaff

A

a=t

g=c

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8
Q

what is the genetic material?

A

DNA

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9
Q

what did Griffith find

A

mice

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10
Q

Avery, macleod carthy

A

isolated and purify the transforming substance.

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11
Q

Hershey Chase experement

A

T2 virus
used radioactive phosphorus and suffer.
phage attacks to wall and injects DNA into cell
it is replicated and then lyses.

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12
Q

is the helix right handed?

A

yes

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13
Q

whats on the outside of the helix?

A

sugars and phosphates

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14
Q

whats on the inside of the helix?

A

bases

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15
Q

primary structure of DNA

A

nucleotide structure and how they are joined

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16
Q

Secondary

A

Stable 3D configuration helical structure

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17
Q

Tertiary

A

complex packing arrangement of double stranded DNA in chromosome.

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18
Q

what is ribose

A

RNA sugar

OH to 2’ carbon

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19
Q

what is Deoxyribose

A

DNA sugar

h to 2’ carbon

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20
Q

What are the types of Nitrogenous base

A

purine

pyrimidine

21
Q

what is purine

A

6 sided right attached to 5 sided ring

22
Q

what is a pyrimidine

A

6 sided ring only

23
Q

Adenine and Guanine are what?

24
Q

Cytosine and thymine and uricel are

A

pyrimidines

25
What has Uricel
RNA
26
what is nucleoside
deoxyribose sugar and base together.
27
what is a phosphate group
phosphorus atom bonded to 4 o atoms.
28
information about a phosphorus atoms
negative charge. DNA is acidic always bonded to 5' carbon of sugar.
29
what are phostodiester linkages
covalent bonds that join 5' to 3'
30
5' end
free phosphate group
31
3' end
OH group attached to 3' carbon of the sugar
32
how are the antiparallel 5-3 bonded?
hydrogen bonds
33
what is the central dogma?
dna is transfered in one direction
34
What is RNA replication
rna to rna
35
What is supercoiling
DNA helix is subject to strain because it is over wound
36
What is positive supercoiling
over rotated
37
what is negative supercoiling
under rotated
38
topoisomerease.. function
enzyme that adds or removes rotations by breaking the nucleotide strands.
39
Does bacteria DNA attach to histone
no
40
What is Euchromatin
normal process of condensation and decondensation in the cell cycle
41
what is Heterochromatin
Highly condensed state through out the cell cycle
42
what are histones
small + charged proteins
43
what does H1 do
locks dan into place and clamps in the nucleosome
44
chromatin structure
Nucleosomes fold on themselves to form tackily packed structures.
45
Centromeres
allow segregation to take place.
46
Telomere structure
Stabalize chromosome
47
What is the C value
amount of DNA per cell. | EUKARYOTES HAVE MORE DNA
48
Unique Sequence DNA
present once or few times in genome | encode proteins
49
what does tandem mean
clusters. | one after the other