Chapter 8 Flashcards
Skin Disorders
Skin functions
Protect against microorganisms
Protect against UV radiation
Prevent loss of body fluids
Protect against mechanical stress
Regulate body temperature
Produce vitamin D
Facilitate sensation
Three layers of skin
Epidermis - Dermis - Subcutaneous (hypodermis)
Epidermis
epithelial tissue and 5 layers
5 layers of Epidermis
A. Stratum basale
B. Stratum spinosum
C. Stratum granulosum
D. Stratum lucidum
E. Stratum corneum
Dermis
consists mainly of connective tissue and contains hair follicles, sebaceous glands, and eccrine glands.
Subcutaneous layer
connective tissue, mostly adipose.
Pruritus
Pain or itching
Biopsy
can help detect a malignancy
Antihistamine
Used to treat pruritus
Why are skin lesions itchy
Bacterial infections and reactions caused by allergens may spur the release of histamines, which can cause inflammation and pruritus, or itching, by stimulating the many sensory nerve endings in the skin. Antihistamines and glucocorticoids may be prescribed to relieve itching, and further pruritus may be prevented with the use of topical antiallergen creams and ointments.
Contact Dermatitis
Exposure to allergen - red edematous skin, direct chemical contact, poison ivy
Urticaria
Hives - Hypersensitivity reaction, erythematoys lesions, can happen in throat
Atopic dermatitis
Eczema - common in infants and can progress to adulthood, inherited tendency towards allergic conditions, dry and scaly (lichenification), eosinophilia
Psoriasis
Chronic inflammation skin disorder, associated with T-cell Activation, keratinocyte proliferation and increased cytokines
Pemphigus
Autoimmune disorder that has various types. causes autoantibodies to disrupt cohesion between epidermal cells causing blider formation and spread
Scleroderma
Purely integumentary or may be systemic affecting viscera. Collagen deposition causes inflammation and fibrosis. hard and shiney skin, can affect face and various other organs
Dupuytrens Contracture
Contraction of finger tissues and results in deformed hands - cause unknown
Which of these characteristics is not descriptive of a furuncle?
a. Typically caused by S. aureus
b. May result in the formation of a carbuncle
c. Often caused by a viral infection
d. May develop into an abscess
C
Which of these characteristics is not descriptive of impetigo?
a. Accompanied by pruritus
b. Caused by Staphylococcus aureus
c. Not typical in infants and children
d. Often requires systemic antibiotics
c
Which of these characteristics is not descriptive of necrotizing fasciitis?
a. Typically caused by a viral infection
b. nvolves such systemic effects as fever, tachycardia, and organ failure
c. May be treated with antimicrobial drugs and excision of tissue
d. May begin as a minor skin trauma or infection
A
Cold Sores
Herpes simplex 1 (mouth) & 2 (genital). presence of blister may give rise to keratitis and can recur with sun exposure
Verrucae
Warts. caused by different strains of HPV. treated with salicylic acid
Tinea capitis
Fungal infection of scalp
Tinea Corpora’s
Fungal infection of body, particularly nonhairy parts
Tinea pedis
Athletes foot
Tinea Unguium
Fungal infection of the nails
Scabies
Caused by mites, burrowing found in webs of fingers and wrists, but can be found anywhere, may cause erythema.
Pediculosis
Caused by lice feeding on blood, infestation is usually in hair and pubic area. topical malathion.
Seborrheic keratosis
Benign tumor caused by basal cell proliferation
Squamous cell carcinoma
May develop from leukoplakia
Develops from melanocytes
Melanoma
associated with HIV infection
Kaposi sarcoma
Sweat glands located all over the surface of the body are called
Eccrine
Although the primary cause of scleroderma is unkown, every case involves the presence of
Collagen deposits
Furuncles are mostly caused by
Staph. aureus
Necrotizing fascitis is mostly caused by
Group A beta-hemolytic streptococcus
most common cause of warts
HPV
scabies is caused by
Mites
seborrheic keratosis is a result of
PRoliferation of basal cells
squamous cell carcinoma is a tumor of the
Epidermis
melanomas develop from
melanocytes
Kaposi sarcoma is associated with
HIV infection
Pediculosis is caused by
Lice