Chapter 7.1-7.2 Flashcards

0
Q

What does RNA stand for

A

Ribonucleic acid

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1
Q

What does DNA stand for

A

Deoxyribonucleic acid

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2
Q

Types of RNA

A

Messenger
Ribosomal
Transfer

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3
Q

tRNA

A

Transfer RNA

Brings amino acids to ribosomes where they are joined together to form proteins

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4
Q

rRNA

A

Ribosomal RNA
Helps form ribosomes, where the proteins are assembled
Anticodon

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5
Q

mRNA

A

Messenger RNA

Copies the genetic instructions from DNA in the nucleus, and carries them to the cytoplasm

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6
Q

DNA

A

Contains genes, instructions for all of the proteins that your body makes
Found in chromosomes

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7
Q

Central dogma of molecular biology

A

DNA > RNA > protein

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8
Q

RNA

A

Carries information of DNA to ribosome and helps assemble the proteins

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9
Q

Chargaff’s rules

A

Concentrations of four bases differ in different species, yet adenine = thymine and guanine = cytosine

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10
Q

What are the four bases

A

Adenine
Thymine
Guanine
Cytosine

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11
Q

Structure of DNA

A

Double helix

Two polynucleotide chains

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12
Q

Who are given credit for discovering structure of DNA

A

Watson and Crick

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13
Q

What does the polynucleotide chain consist of

A

A sugar
A phosphate group
A nitrogen containing base (a,t,g,c)

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14
Q

How are the two polynucleotide chains held together in DNA

A

Hydrogen bonds

Bonds between A-T, and G-C

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15
Q

DNA replication

A

Process in which DNA is copied
Occurs during S (synthesis) phase
Enzyme breaks bonds between two polynucleotide chains of parent molecule
Other enzyme pairs new, complementary nucleotide with those in the two parental chains
Two daughter DNA molecules form, each containing one new chain

16
Q

RNA vs. DNA

A

RNA- smaller, one nucleotide chain, contains uracil (U) instead of thymine, contains sugar ribose instead of deoxyribose

17
Q

Where are proteins made

A

On the ribosomes in the cytoplasm

18
Q

Who first concluded that DNA is the genetic material in cells

A

Oswald Avery

19
Q

Who confirmed that DNA is the genetic material

A

Hershey and Chase

20
Q

Protein synthesis

A

The process in which cells make proteins
Transcription-nucleus
Translation-ribosome

21
Q

Transcription

A

DNA > RNA
Initiation
Elongation
Termination

22
Q

Initiation (Transciption step 1)

A

Enzyme polymerase binds to region of gene called promoter
This signals DNA to unwind so the enzyme can read the bases in one of the DNA strands
The enzyme is ready to make a strand of mRNA with a complementary sequence of bases

23
Q

Elongation (Transcription step 2)

A

Addition of nucleotides to the mRNA strand

24
Termination (Transcription step 3)
mRNA strand is complete and it detaches from the DNA
25
Triplet
Group of three successive nucleotide bases in DNA
26
Codon
Group of three nucleotide bases in mRNA that corresponds with the triplet
27
Why process mRNA more before it leaves the nucleus in eukaryotes?
It allows a single gene to be used to make more than one protein
28
Splicing
Removes introns from mRNA Introns are regions that don't code for proteins Then it consists of only exrons, which are regions that do code for proteins
29
Editing
Changes some of the nucleotides in mRNA
30
Polyadenylation
``` Adds a "tail" to the mRNA Tail consists of string of adenine bases Signals end if mRNA Involved in exporting mRNA from nucleus Protects mRNA from enzymes that might make it break down ```
31
Genetic Code
Consists of bases A,T,G,C Letters grouped to form codons Each codon stands for one amino acid/stop/start 20 common amino acids, 64 possible codons
32
Stop codons
UAG UGA UAA
33
Start codon
Aug- methionine
34
Characteristics of genetic code
Universal-all living things have same genetic code Unambiguous-each codon codes for just one amino acid/start/stop Redundant-most amino acids are coded by more than one codon
35
Translation
RNA > Protein mRNA moves to ribosomes high reads sequence, tRNA brings corresponding amino acids Bonds form between amino acids, forming polypeptide chain, which keeps growing until a stop codon is reached May assume folded shape, bond with other polypeptides or molecules, and many go to Golgi apparatus to be modified for specific job they will do