Chapter 7 Membrane structure and Function Flashcards
Amphipathic
Having both a hydrophilic region and a hydrophobic region
Fluid Mosaic Model
cell membrane structure, which envisions the membrane as a mosaic of protein molecules drifting laterally in a fluid bilayer of phospholipids
Integral Proteins
A transmembrane protein with hydrophobic regions that extend into and often completely span the hydrophobic interior of the membrane and with hydrophilic regions in contact with the aqueous solution on one or both sides of the membrane (or lining the channel in the case of a channel protein)
Peripheral Proteins
A protein loosely bound to the surface of a membrane or to part of an integral protein and not embedded in the lipid bilayer
Glycolipids
A lipid with one or more covalently attached carbohydrates
Glycoproteins
A protein with one or more covalently attached carbohydrates
Transport Protein
A transmembrane protein that helps a certain substance or class of closely related substances to cross the membrane
Aquaporins
A channel protein in a cellular membrane that specifically facilitates osmosis
Diffusion
movement of a substance from a region where it is more concentrated to a region where it is less concentrated
Concentration gradient
A region along which the density of a chemical substance increases or decreases
Passive Transport
The diffusion of a substance across a biological membrane with no expenditure of energy
Osmosis
The diffusion of free water across a selectively permeable membrane
Tonicity
The ability of a solution surrounding a cell to cause that cell to gain or lose water
Isotonic
a solution that when surrounding a cell, causes no net movement of water into or out of the cell
Hypertonic
a solution that when surrounding a cell, will cause the cell to lose water
Hypotonic
a solution that when surrounding a cell, will cause the cell to take up water
Turgid
Swollen or distended, as in plant cells. (A walled cell becomes turgid if it has a lower water potential than its surroundings, resulting in entry of water.)
Flaccid
Limp. Lacking turgor (stiffness or firmness), as in a plant cell in surroundings where there is a tendency for water to leave the cell. (A walled cell becomes flaccid if it has a higher water potential than its surroundings, resulting in the loss of water.)
Osmoregulation
regulation of solute concentrations and water balance by a cell or organism
Plasmolysis
in walled cells in which the cytoplasm shrivels and the plasma membrane pulls away from the cell wall; occurs when the cell loses water to a hypertonic environment
facilitated diffusion
The passage of molecules or ions down their electrochemical gradient across a biological membrane with the assistance of specific transmembrane transport proteins, requiring no energy expenditure
Ion channel
A transmembrane protein channel that allows a specific ion to diffuse across the membrane down its concentration or electrochemical gradient
Gated channel
A transmembrane protein channel that opens or closes in response to a particular stimulus
Active transport
The movement of a substance across a cell membrane against its concentration or electrochemical gradient, mediated by specific transport proteins and requiring an expenditure of energy
Sodium-Potassium pump
A transport protein in the plasma membrane of animal cells that actively transports sodium out of the cell and potassium into the cell
Membrane potential
The difference in electrical charge (voltage) across a cell’s plasma membrane due to the differential distribution of ions. Membrane potential affects the activity of excitable cells and the transmembrane movement of all charged substances
Electrochemical gradient
The diffusion gradient of an ion, which is affected by both the concentration difference of an ion across a membrane (a chemical force) and the ion’s tendency to move relative to the membrane potential (an electrical force)
Electrogenic pump
An active transport protein that generates voltage across a membrane while pumping ions
Proton pump
An active transport protein in a cell membrane that uses ATP to transport hydrogen ions out of a cell against their concentration gradient, generating a membrane potential in the process
Cotransport
The coupling of the “downhill” diffusion of one substance to the “uphill” transport of another against its own concentration gradient
Exocytosis
The cellular secretion of biological molecules by the fusion of vesicles containing them with the plasma membrane
Endocytosis
Cellular uptake of biological molecules and particulate matter via formation of vesicles from the plasma membrane
Phagocytosis
A type of endocytosis in which large particulate substances or small organisms are taken up by a cell. It
is carried out by some protists and by certain immune cells of animals (in mammals, mainly macrophages, neutrophils, and dendritic cells)
Pinocytosis
A type of endocytosis in which the cell ingests extracellular fluid and its dissolved solutes
Rector- Mediated endocytosis
The movement of specific molecules into a cell by the infolding of vesicles containing proteins with receptor sites specific to the molecules being taken in; enables a cell to acquire bulk quantities of specific substances