Chapter 7 - Mass transport Flashcards
what is the quarternary structure of haemoglobin?
four polypeptides, each associated with a haem group which contains Fe 2+ which can combine with one molecule of oxygen each
what is the term for taking up oxygen in haemoglobin?
loading and unloading
what is the role of haemoglobin? (2)
- readily associate with oxygen at gas exchange (high partial pressure)
- readily dissociate at low partial pressures such as respiring tissues
why are their different haemoglobin in different animals?
different partial pressure e.g. high altitude
different dissociating required e.g. lugworms
explain the shape of oxygen dissociation curves (4)
- difficult for first molecule to bind = shallow curve gradient
- first molecule binding changes the shape making it easier for subsequent molecules to bind
- positive cooperativity, the gradient steepens
- lower probability of oxygen binding when oxygen is highly loaded means gradient levels off
what are the effects of CO2 on haemoglobin? (3)
- reduced affinity for oxygen
- release oxygen more readily at high CO2 conc. ,e.g. respiring tissues
- slightly acidic, CO2 changes shape of haemoglobin
state the sequence of vessels in the heart from the vena cava to the aorta (12)
- vena cava
- right atrium
- atrioventricular valve
- right ventricle
- semi-lunar valve
- pulmonary artery
- (lungs)
- pulmonary vein
- left atrium
- atrioventricular valve
- left ventricle
- semi-lunar valve
- aorta
name the 3 stages of the cardiac cycle
diastole
atrial systole
ventricular systole
what are the valves in veins and what do they do?
pocket valves prevent backflow
what is the action of diastole? (3)
- blood returns to atria through vena cava and pulmonary vein
- when pressure exceeds that in the ventricles the semi-lunar valves open allowing blood to drain into ventricles by gravity
- semi-lunar valves remain open until the pressure in the atria has decreased below that of the ventricles
what is the action of atrial systole?
both atria contract at the same time along with further recoil of the ventricles, forcing the remaining blood in the atria into the ventricles
what is the action of ventricular systole? (2)
- ventricles contract together, AV valves shut
- pressure within ventricles rises further forcing the semilunar valves of aorta open due to higher pressure in ventricles
- (creates high pressure for blood to go round whole body and back)
state the cardiac output calculation
heart rate x stroke volume = cardiac output
name the types of blood vessels (4)
- arteries
- arterioles
- capillaries
- veins
what are capillaries made from?
lining layer/epethelial cells