Chapter 4 - Transport across cell membranes Flashcards

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1
Q

what is the structure of a phospholipid? (2)

A

hydrophillic head - phosphate

hydrophobic tail - fatty acids

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2
Q

function of phospholipid bilayer? (3)

A
  • allow lipid soluble substances through
  • prevent water soluble substances
  • make membrane flexible and self sealing
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3
Q

what is the purpose of extrinsic proteins? (2)

A
  • mechanical support

- with glycolipids act as cell receptors

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4
Q

purpose of intrinsic proteins? (4)

A
  • channels, water soluble molecules
  • cell surface receptors for identification/hormones
  • structural support
  • help cells adhere together
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5
Q

features of cholesterol? (2)

A
  • very hydrophobic

- pull together tails of phospholipids of bilayer

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6
Q

functions of cholesterol? (3)

A
  • reduce fluidity of phospholipids and other molecules
  • make membrane more rigid at high temperatures
  • prevent water leakage/dissolved ions
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7
Q

functions of glycolipids? (3)

A
  • recognition sites
  • stability of membrane
  • formation of tissues - attach together
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8
Q

functions of glycoproteins? (3)

A
  • cell recognition sites
  • form tissues
  • allows cells to recognise one another
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9
Q

why are most molecules not able to diffuse across the phospholipid bilayer? (4)

A
  • not lipid soluble
  • too large
  • charged
  • same charges as protein channels
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10
Q

why is it important for the cell surface membrane to remain fluid?

A

flexibilty, able to change shape

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11
Q

definition of diffusion?

A

net movement of molecules from a region of high conc. to region of low conc.

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12
Q

define facilitated diffusion

A

diffusion involving proteins to allow large/charged molecules across plasma membranes

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13
Q

definition of osmosis?

A

passage of water from area of high water potential to are of low water potential through a selectively permeable membrane

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14
Q

what is the water potential of pure water?

A

0kPa

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15
Q

what is active transport?

A

movement of molecules/ions from region of low - high conc. using ATP and carrier proteins

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16
Q

process of active transport? (4)

A
  • molecule binds to carrier
  • ATP binds on outside of cell to carrier protein then splits
  • causes carrier to change shape and molecule released in cell
  • phosphate + ADP released and carrier reverts to original shape
17
Q

how is the rate of movement across membranes in the ileum maximised? (2)

A
  • microvilli

- high quantities of carrier/channel proteins

18
Q

how is a favourable conc. gradient maintained in the ileum? (3)

A
  • constant digestion or carbs
  • continuous blood flow, extensive capillary network
  • facilitated diffusion
19
Q

outline co-transport in the ileum (4)

A
  • sodium ions actively transported out of epethelial cells into blood
  • higher conc. in lumen
  • sodium ions diffuse down gradient through co-transport channels carrying with it amino acids or glucose
  • glucose/amino acids pass into blood by facilitated diffusion