Chapter 7 Flashcards
Frederick Griffiths
created transformation principle
Avery, McCarty, MacLeod
They found out DNA is transforming agent by destroying lethal DNA with DNAse and that is the only rat that survived.
Hershey and Chase
found out that DNA was the material that phages use by using phosphorous isotope to coat DNA and that stayed in cells when phages were gone
Rosalind Franklin and Wilkins
She did the x-ray crystallography of DNA but she was not able to make heads or tails of it.
Chargaff
He figured out that every adenosine pairs with a thyamine as well as G and C.
James Watson, Frances Crick
They “found” crystallography photos. with that info and other info like chargaffs ratio and linus pauling’s alpha helix proteins, they build the DNA model.
Messelson and Stahl
discovered semiconservative replication
Eukaryotic DNA polymerase (Alpha)
Initiates DNA replication in conjunction with with primase
Eukaryotic DNA polymerase (epsilon)
replication of leading strand during S phase
Eukaryotic DNA polymerase (Delta)
replication of lagging strand during S phase
Eukaryotic DNA polymerase (Upsilon)
replication of mitochondrial DNA