Chapter 7 Flashcards

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1
Q

What is nicotine? What is tobacco used for?

A

Nicotine has only one natural source—tobacco plant. Tobacco is used for smoking—cigarettes, cigars, or pipes

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2
Q

How toxic is nicotine?

A

As toxic as cyanide

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3
Q

Who discovered tobacco? Who had a monopoly on it?

A

Western Europeans discovered tobacco. Spanish had a monopoly

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4
Q

When was nicotine’s toxic properties discovered?

A

By 1860, it was accepted that it was not medicinal as nicotine’s toxic and addictive properties were discovered

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5
Q

What is the most common way to use tobacco?

A

Cigarettes are the most common way to use tobacco

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6
Q

When was smoking’s peak?

A

It’s “peak” is considered to be 1963 and has been in decline since.

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7
Q

Who are the highest percent of smokers?

A

People aged 18-25 represent the
highest percentages of smokers.

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8
Q

The ____ someone starts to smoke, the ____ it is for them to quit later.

A

The younger someone starts to smoke, the harder it is
for them to quit later.

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9
Q

What ages are more likely to use smokeless tobacco use?

A

Smokeless tobacco use: most popular among 18–25 year olds

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10
Q

What gender is 10% more likely to use smokeless tobacco?

A

men are 10 times more likely than women to use smokeless tobacco.

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11
Q

What is a cholinergic agonist that has biphasic actions?

A

Nicotine is a cholinergic agonist that has biphasic
(stimulant and depressant) actions.

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12
Q

What are the effects of acetylcholine (nicotine)?

A

Increases blood pressure, increases heart rate, stimulates the release of adrenalin, increases movement of GI tract, release of dopamine and seretonin

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13
Q

Where is nicotine readily absorbed through?

A

Readily absorbed through the oral, buccal, and nasal
mucosa; the gastrointestinal tract; and the lungs.

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14
Q

Where does nicotine absorb the fastest?

A

Absorption through the lungs is fastest.

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15
Q

What is post-inhalation?

A

nicotine reaches the brain in seven seconds; then is quickly distributed to other sites of action (peak levels at about 3- 5 minutes).

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16
Q

What is the primary organ for metabolizing nicotine?

A

Liver: primary organ for metabolizing nicotine.

17
Q

How do you “eliminate” nicotine?

A

Elimination: mostly in urine; about 10-20% is eliminated unchanged

18
Q

_____ to nicotine develops quickly. High ____ after a few

A

Tolerance to nicotine develops quickly. high tolerance even just after a few

19
Q

Nicotine includes physical _____: a drop enough in ____ levels includes physical symptoms and only re-administration relieves them.

A

Nicotine induces physical dependence: a drop enough in blood levels induces physical symptoms and only re- administration relieves them

20
Q

What are the acute effects of nicotine?

A

Increases body activity while resting, reduced activity in different neurons, initiates dilation, increases vomiting activity, decreases taste of (sweet) food

21
Q

How does smoking kill?

A

the smoker’s chronic exposure to carbon monoxide, tar, and nicotine in tobacco smoke.

22
Q

How many deaths in the US per yr are attributed to smoking?

A

480,000 deaths each year in the United States are attributable to smoking

23
Q

What is required on cigarette packaging per 1984 law?

A

Surgeon General text warning

24
Q

What are the main 3 health problems causing culprits?

A

tar, nicotine, and carbon monoxide

25
Q

What does carbon monoxide specifically cause?

A

disease-causing

26
Q

What does tar specifically cause?

A

Cancer-causing

27
Q

What are major diseases linked to smoking?

A

heart disease, chronic obstructive lung disease, cancers of various types

28
Q

What are major reasons for relapsing smoking?

A

smokers continue to crave nicotine long after they have stopped smoking.