Chapter 6: Nomenclature Flashcards

1
Q

True/false: Cancer is a genetic disorder caused by DNA mutations.

A

True, this can be due to exposure of mutagens, aging

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2
Q

Are genetic alteration in cancer cells heritable?

A

Yes (they are passed from mother-daugher cells)

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3
Q

Mutations and epigenetic alterations impart to cancer cells a set of properties. How are they collectively referred to?

A

Cancer hallmarks

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4
Q

What does neoplasia mean?

A

New growth

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5
Q

Why are neplastic cells said to be transformed?

A

Because they continue to replicate

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6
Q

What does oncos mean?

A

tumor

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7
Q

Is neoplasm the same as a tumor?

A

Jep

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8
Q

When is a tumor considered benign?

A

A tumor is said to be benign when its microscopic
and gross characteristics are considered to be rela- tively innocent, implying that it will remain localized and is amenable to local surgical removal.

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9
Q

When is a tumor considered malignant?

A

Malignant, as applied to a neoplasm, implies that the lesion can invade and destroy adjacent structures and spread to distant sites (metastasize) to cause death.

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10
Q

Is a benign/malignant tumor called cancer?

A

Only malignant is referred to as cancer

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11
Q

All tumores, benign and malignant, have two basic components. Which two?

A

(1) the parenchyma, made up of transformed or neoplastic cells, and (2) the supporting, host-derived, non-neoplastic stroma, made up of connective tissue, blood vessels, and host-derived inflammatory cells

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12
Q

What are the (overall) differences between benign vs malignent?

A

Benign:

  • small
  • well demarcated
  • well differentiated
  • slow growing
  • noninvasive
  • nonmetastic

Malignant:

  • large
  • poorly demarcated
  • poorly differentiated
  • rapidly growing
  • locally invasive
  • metastatic
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13
Q

Does the suffix -oma mean that a cell is benign or malignant?

A

Benign

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14
Q

What is an adenoma?

A

An adenoma is a benign tumor of epithelial tissue with glandular origin, glandular characteristics, or both

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15
Q

What are papillomas?

A

Benign epithelial neoplasms, growing on any surface, that produce fingerlike fronds

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16
Q

What is a polyp?

A

A mass that projects above a mucosal surface (e.g. gut)

17
Q

Are all polyps benign?

A

No

18
Q

Malignant neoplasms arising in “solid” mesenchymal

tissues or its derivatives are called…

A

sarcomas

19
Q

Malignant neoplasms arising from the mesenchymal cells of the blood are called….

A

leukemias or lymphomas

20
Q

Sarcomas are designated based on their cell-type composition, that reflects the cell of origin. Name some

A

fat-like cells is a liposarcoma,

chondrocyte-like cells is a chondrosarcoma

21
Q

How are malignent neoplasms of epithelial cells called?

A

Carcinomas (so this includes ecto-, meso- and endoderm!)

22
Q

What are adenocarcioma’s?

A

carcinomas (of epithelial origin) that grow in a glandular pattern