Chapter 6 adaptive quiz Flashcards
Extensive _____ trimming is more common at the _____ heavy-chain V gene joints than at the light-chain V-J joint.
exonuclease, two
Cells destined to become αβ T cells proceed to the DP stage where they are tested for their ability to recognize antigen displayed by immune system cells (_____ selection) without inducing autoimmunity (_____ selection).
positive, negative
Like the heavy chain, the light chain:
can be rearranged on both homologous chromosomes.
Only three of the proteins implicated in VJ recombination are unique to lymphocytes: _____, _____, and terminal deoxynucleotidyl transferase.
Rag 1 and Rag 2
In both heavy and light chains:
the number of V regions is greater than the number of J regions.