chapter 12

Question 1

polymeric immunoglobulin receptor (polyIgR)

Answer 1

FcR expressed by epithelial cells that initiates the transcytosis (endocytosis and transport) of IgA and IgM across the epithelial layer, from the blood and underlying tissue to the lumen (the inside of passageways or ducts) of mucosal and glandular tissues.

igA is the main class transported into secretions

Question 2

_____ is responsible for carrying IgG antibodies ingested from mother’s milk across epithelial cells of an infant’s intestine to the bloodstream—the _____ direction of the antibodies carried by the polyIgR.

Answer 2

FcRn; opposite

Question 3

Compared to CTLs, NK cells

Answer 3

can kill target cells via ADCC.

Question 4

All of these statements describe IgG antibodies EXCEPT:
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Answer choices

They are the most abundant serum antibody.

They are the most diverse class of antibody.

They are capable of complement fixation.

They are mediators of antibody-dependent cell cytotoxicity (ADCC).

All of the statements describe IgG antibodies.

Answer 4

All of the statements describe IgG antibodies.

Question 5

Which of these is NOT an effector function of antibodies?
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Answer choices

Targeting for lysis by complement

Prevention of viral entry into cells

Targeting for lysis by natural killer cells

Blockage of bacterial toxin secretion

Targeting for phagocytosis

Answer 5

Blockage of bacterial toxin secretion