Chapter 6 Flashcards
What is the cell cycle
Ordered sequence of events
That takes place in a cell
Resulting in division
And formation of two identical daughter cells
What occurs during interphase
Cell grows
Organelles and proteins are made
DNA is replicated and checked for errors
Mitochondria and chloroplasts grow and divide in the cytoplasm
Metabolic processes of cells occur
G1
Proteins from which organelles are made from are produced
Organelles and replicates
S
DNA is replicated
G2
Energy stores are increased
DNA replication errors checked
Proteins made for cell division
Cell division involves 2 stages
Mitosis - nuclear division
Cytokinesis - cytoplasmic division
What is Go
Phase when the cell leaves the cycle permanently or temporarily
Why would the cell need to leave the cell cycle
Differentiation
- a cell becomes specialised to carry out a particular function indefinitely, it won’t need to divide
DNA
- dna may be damaged
Cells become senescent and are only able to divide a limited number of times
What is the point of checkpoints
They are the control mechanisms of the cell cycle
Moniteur and verify whether each stage has been accurately completed before progressing
What do checkpoints mainly check for
Cell only divides when it as grown to the right size
DNA damage
DNA replication error free
Chromosomes are attached to spindle fibres and aligned
Why is mitosis needed
For growth
Repairing damaged tissues
Asexual production
What does mitosis produce
Two genetically identical daughter cells
Interphase mitosis
Each chromosome is converted into two identical dna molecules called chromotids that are joined at the centromere - which keep the chromotids together during mitosis to make sure one of each is in the new daughter cells
Mitosis in root tips of plants
Treated with a chemical to allow the cells to be separated
Squash slides to form single layer of cells
Stained
Prophase mitosis
- Chomotin fibres coil and condensé to form chromosomes that will take up stain and become visible
- protein microtubules (centrioles) move to opposite ends of pole, form a network of protein fibres called spindle
- the fibres forming the spindle allow movement of chromosomes
- spindle fibres attach to centromere
- nuclear envelope breaks down
Metaphase mitosis
- chromosomes are moved by the spindle fibres to form a plane in the centre of the cell
- called the metaphase plate
Anaphase mitosis
- centromeres divide
- chromatids are separated and pulled to opposite sides due to shortening spindle fibres
Telophase mitosis
- chromatids reach poles
- they uncoil and become long and thin ( chromosomes)
- nuclear envelope forms around each set of chromosomes
Cytokinesis mitosis
Animal cells
Cleavage furrow forms around the middle of the cell
Cell surface membrane is pulled inwards by the cytoskeleton until it fuses around the middle
Forming 2 cells
Cytokinesis mitosis
Plant cells
Vesicles from Golgi apparatus assemble on the metaphase plate and fuse together and with the cell surface membrane
Dividing the cell in two
New plant cell wall is formed
Otherwise osmotic lysis
What is the purpose of meiosis
Happens in the reproductive organs to produce gametes
Genetically different
Haploid
Reduction division
What are homologous chromosomes
Matching pairs of chromosomes, one chromosome in the 23 pairs is a maternal chromosome and the other is paternal.
Contain the same genes at the same loci, but with a variation of those genes called alleles
Meiosis 1
Reduction division
Homologous chromosomes are separated into 2 cells
Each intermediate cell will contain a full set of genes instead of 2 = haploid
Meiosis 2
Pairs of chromatids in daughter cell are separated
4 haploid daughter cells
Prophase 1 meiosis
Chromosomes condense
Nuclear envelope disappears
Spindle formation begins
- Homologous chromosomes pair up forming bivalents
- Chromatids entangle, called crossing over
Metaphase 1 meiosis
Homologous pairs assemble on the metaphase plate
Attach to the spindle fibres via their centromeres
Independent assortment
In meiosis
Metaphase 1
Homologous pairs line up randomly along the metaphase plate
Maternal or paternal chromosomes can face either pole
Is a random process
Results in many different combinations of alleles facing the poles which results in genetic varaitaion
Anaphase 1 meiosis
Homologous chromosomes are pulled to opposite poles, chromatids stay joined
Sections of dna on chromatids that had become entangled during crossing over, break off and rejoin, resulting in a exchange of DNA
What is chiasmata
The points which the chromatids break and rejoin
What are recombinant chromatids
Anaphase 1 meiosis
Sister chromosomes that are now genetically different and no longer copies
Creates genetic variation
Caused by genes being exchanged
Telophase 1 meiosis
Nuclear membrane reforms
Chromosomes uncoil
Cytokinesis is the same as mitosis
Prophase 2 meiosis
Chromatids condense and become visible
Envelope breaks down
Spindle fibres form