Chapter 6 Flashcards
1
Q
Which types of malignant neoplasia have been associated with human papilloma virus?
A
cervix, vulva, anal canal, head and neck
2
Q
Which part of the papillomavirus interact with PFGFR?
A
E5
3
Q
How does the papillomavirus affect P53 function in the cell?
A
E6 is an ubiquitin ligase, ultimately resulting in degradation of p53
4
Q
How does the presence of papillomavirus influence the function of pRb?
A
E7 binds pRB, which targets pRB for degradation.