Chapter 5_Anxiety, OCD, Trauma, Stressor Related Disorders Flashcards
General way to treat anxiety?
Milder: psychotherapy
Moderate to severe: psychotherapy + combination pharmacotherapy
severity is gauged based on amount of distress/impairment
What medications/substances cause anxiety?
alcohol (toxication and withdrawal), sedatives, hypnotics withdrawal, cannabis, hallucinogens, stimulants, caffeine, tobacco, opioid withdrawal
What medical conditions cause anxiety?
neuro: epilepsy, migrianes, brain tumors, MS, Huntingons
endocrine: hyperthyroid, thyrotoxicosis, hypoglycemia, pheochromocytoma, carcinoid syndrome
metabolic: vitamin b12 deficiency, electrolyte abnormalities
respiratory: asthma, COPD, hypoxia, PE
CV: CHF, angina, arrhythmia
What NT systems are implicated in anxiety?
NE, serotonin, and GABA
First line pharmacotherapy for anxiety?
SSRIs (sertraline) and SNRIs (venlafaxine)
low doses for depression
HIGHER DOSES FOR ANXIETY
How are benzodiazepines involved in treatment of anxiety?
Enhance GABA activity, but can be ADDICTIVE! Only use this to temporarily bridge patients until long term medication can be used. Avoid in patients with comorbid substance use
What are some nonaddicting PRN anxiolytics?
diphenhydramine (benadryl), hydroxyzine (atarax)
Beta-blockers (propanolol) can also be useful in treating anxiety; especially in….?
controlling autonomic symptoms (palpitations, tachycardia, sweating)
also for PANIC ATTACKS AND PERFORMANCE ANXIETY
Use B’s to Block P’s (Panic attacks, and Performance anxiet)
When should benzodiazepines be avoided?
Patients with comorbid substance use disorder and depression disorder (may worsen depression)
What is the pharmalogic goal of anxiety treatment?
achieve symptomatic relief for at least 6 months before tapering off meds, or at least until therapy can be initiated
What two types of therapy are useful for anxiety treatment?
CBT (relationship between anxiety driven cognitions/thoughts, emotions, and behavior)
psychodynamic psychotherapy - insight into development of anxiety and increases tolerance
Panic attacks
type of fear response involving sudden anxiety surge (spontaneous or from trigger). Peak within minutes and resolve within half an hour.
Symptoms: dizziness, disconnectedness, depersonalization, palpitations, paresthesias, abdominal distress, numbness/nausea, intense fear of dying or losing control, chills, sweating, SOB
DSM criteria for panic disorder
- Recurrent and UNEXPECTED panic attacks without identifiable trigger
- one or more panic attacks followed by at least one month of continuous worry of FUTURE panic attack
- not due to substance/medical condition
When patient presents with panic attack, what to rule out?
MI, thyrotoxicosis, and thromboembolism
Treatment for panic disorder
Pharmacotherapy (first line SSRIs like sertraline (zoloft) citalopram (celexa), or escitalopram (lexapro) then TCAs if not effective or PRN benzos) PLUS CBT
What other psych disorders are often comorbid with anxiety
Major depression, other anxiety disorders, bipolar disorder, and alcohol use disorder
DSM criteria for agoraphobia
- Intense fear/anxiety of >2 situations for concern of difficulty escaping/accessing help in case of panic disorder/embarassing situation (i.e. outside of home alone, open spaces, enclosed places, public transport, crowds)
- fear out of proportion to trigger, usually involving prolonged anxiety, need for companion, or avoidance
- symptoms last longer than 6 months
- significant impairment
- not due to any other disorder/substance
What are some characteristic situations avoided in agoraphobia?
Bridges, crowds, buses, trains, open areas outside of home
Treatment of agoraphobia?
Same as panic disorder (SSRIs and CBT)
DSM criteria for specific phobia
- Persistent, excessive fear of specific situation or object which is out of proportion
- exposure to trigger = IMMEDIATE fear response
- symptoms lasting more than 6 months