Chapter 5: Peripheral Nervous System Flashcards
the PNS:
contain nerve fivers that carry information between the CNS and other parts of the body.
PNS is diveded into the ____ and ____ division
1) afferent: forward carrying signals towards the CNS.
2) efferent: transmits instructions from CNS to effector organs. Heavily utilizes Ach and Ne
3 components of the efferent division
1) autonomic NS: innervates smooth muscle, cardiac, glands and involuntary organs.
2) somatic NS: consists of fibers of motor neurons that supply skeletal muscles, controls reflects and non reflex skeletal muscle actions.
3) enteric NS: extensive nerve network in the wall of the digestive tract that works with the Autonomic SN and hormones to control digestive activites.
the ___ neurons are mainly in the PNS. Their cell bodies are located near the dorsal root ganglion of the spinal cord, and they contain a sensory receptor at the peripheral end that generates an AP in response to a stimulus
afferent neurons. they convey info from outside (collected by sensory receptors), and transmits it to the CNS.
For Efferent (and thus autonomic neruons) have their cell bodies originating near the ___ ___ of the CNS, and their axon terminals leave to innervate ___ or ___
For Efferent (and thus autonomic neruons and somatic and enteric neurons) have their cell bodies originating near the VENTRAL ROOT HORN of the CNS, and their axon terminals leave to innervate MUSCLES or GLANDS
the autonomic nervous system is part of the ____ division of the PNS, and is further divided into the ___ and ___ systems.
the autonomic nervous system is part of the EFFERENT division of the PNS, and is further divided into the SYMPATHETIC and PARASYMPATHETIC systems.
describe dual innervation
any gland or muscle that is contolled by the autonomic nervous system is undercontrol of the sympathetic AND Parasympathetic nervous system at the same time.
the dual innervation PS and S systems act as an ____ ____ feedback system
antagonistic negative feedback system, they often exert generally the opposite effects.
what is parasymp or symp dominance?
usually, there is both sympathetic and para symp activity occuring at the same time on a gland/effector. But when one system takes over, that is called dominance
describe the general autonomic nerve pathway. What is the exception to this?
each autonomic nerve pathway consists of a 2-neuron chain. The PREGANG fiber (an efferent fiber) originates in the CNS, and synapses with the POST GANGLIONIC fiber in an AUTONOMIC GANGLIA OUTSIDE of the CNS.
All parts of the autonomic nervous system has a 2-neuron chain except the adrenal medulla, in which the preganglion neuron originating in the CNS synapses directly onto the medulla.
the post ganglionic fiber of the Autonomic nervous system pathway has axonal _____, which:
axonal varicosities: bulges in the axon that has the ability to release neurotransmitters and neuromodulators to a LARGE area on an effector
the hypothalamic pituitary adrenal axis in part of the ____ nervous system of the autonomic NS
sympathetic nervous system
the HPA axis is stimulated by ____, causing the hypothalamus to release ____, which moves to the pituitary gland to trigger the release of _____. _____ stimulates the adrenal galnd, promoting ___ and ___ release.
the HPA axis is stimulated by STRESS, causing the hypothalamus to release CTH, which moves to the pituitary gland to trigger the release of ACTH. ACTH stimulates the adrenal galnd, promoting CORTISOL and CATECHOLAMINE release.
which catecholamines are typically released by the HPA axis?
primarily epinephrine and NE. ( mostly epinephrine)
In terms of the HPA axis, what is the secondary response? primary response? tertiary response?
pirmary response: release of cortisol and catecholamines in response to the hypothalamus detecting stress
secondary response: the effects of cortisol and epinephrine (effects metabolic nutrients, the ion concentration gradients etc.)
tertiary response: change in the whole organism (ex/ growth, disease resistance, behavior)
Allostasis
the process by which the body responds to stressors to regain homeostasis. NOT ENTANTOSTASIS, which is the maintenance of systems outside of homeostasis.
physiological definition of acute stress. is this normal?
acute stress is a stressor that elevates heart rate but later moves down to normal levels after the stress is gone. this is evolutionarily normal and it is expected that the body will maintain reactive homeostasis.
reactive homeostasis
the general range of homeostasis that allostasis tries to maintain.
T/F: the stress response is adaptive
true. but we have not yet evolved to manage chronic stress.
why is chronic stress so bad for us?
we have not yet evolved to manage chronic stress, resulting in frequent homeostatic overload because our allostatic mechanisms do not know what to do. this results in increase obesity, cvd and cancer.
the system that promotes general housekeeping activities such as digestion and urination
parasympathetic nervous system. works unconcsiously, many organs are at rest.
Affect of the PS and S on the heart
PS: decreased heart rate, decreased force of contraction
S: increased heart rate, increased force of contraction (Beta 1)
Affect of Ps and S on blood vessesl
PS: dilation
S: vasocontriction A1 (excitatory)
AFfect of PS and S on lungs
PS: CONTRICTION of bronchioles, stimulation of mucus secretion
S: Dilation of broncioles (B2), prevention of mucus secretion (alpha)
Affects of PS and S on digestive tract. What happens to the sphincters?
PS: stimulation of digestion, opening of the sphincters
S: inhibition of digestion (A2B2), closing of the sphincters (A1)
affect of Ps and S on gall bladder
PS: contraction (because the contents are needed for digestion)
S: Relaxation
Affects of Ps and S on bladder
PS: Constriction (makes you pee)
S: relaxation (no peeing)
Affects of Ps and S on eye. What happens to vision?
ps; Constriction of pupil, meant to see things close by
S: dilation of pupil (alpha 1), meant to see things far away.
Affects of PS and S on liver.
PS: NONE
S: glycogenolysis (B2)
Affects of PS and S on adipocytes
PS: none
S: lipolysis (B2)
Affects of PS and S on pancreas
PS: stimulation of pancreatic exocrine secretion (important for digestion
S: inhibition of pancreatic exocrine secretion (A2)