Chapter 5 DNA and Chromosome

Question 1

What is a nucleosome?

Answer 1

Basic structural unit of DNA packaging in eukaryotes
- Segment of DNA wound around a eight histone proteins and resembles thread wrapped around a spool.
- Fundamental subunit of chromatin

Question 2

What comptent is the core of the nucleosome?

Answer 2

Octameric histone core (Histone Octamer): 2x (H2A-H2B) dimers, (H3-H4)^2 tetramer

Question 3

Approximate bp of DNA in a nucleosome?

Answer 3

~150bp

Question 4

What is the fifth histone?

Answer 4

Linker Histone H1, binds to the DNA between adjacent nucleosomes

Question 5

What bonds does DNA and proteins in a nucleosome use?

Answer 5

Ionic bonds. Due to the negatively charged DNA bc of phosphate group, to positively charged molecules