Chapter 15 Endomembrane System

Question 1

What are Chaperone proteins

Answer 1

Help proteins fold properly

Question 2

Deleting the signal sequence from an ER protein does what?

Answer 2

Converts it into a cytosolic protein

Question 3

How are proteins destroyed if damaged?

Answer 3

Addition of Ubiquitin

Question 4

What happens to a polypeptide being translocated across a membrane and hits a stop0transfer sequence?

Answer 4

Stop-transfer sequence anchors the protein in the membrane

Question 5

Describe the best pathway for a protein from synthesis to secretion.

Answer 5

Cytosol-> ER-> transport vesicle-> Golgi -> transport vesicle -> plasma membrane

Question 6

What organelles make up the endomembrane system?

Answer 6

Endoplasmes reticulum, Golgi, endossâmes, lysosomes, and peroxisomes

Question 7

What are the two major covalent medications in the ER?

Answer 7

Disulfide bonds and branched oligosaccharide

Question 8

Disulfide bond function in ER?

Answer 8

Bond cysteines to stabilize protein structure

Question 9

Branched oligosaccahride function?

Answer 9

Added to proteins and matured in Golgi to produce glycoprotein structure