Chapter 4.6 Bidirectional Replication and the Replisome Flashcards
1
Q
DNA synthesis is bidirectional in prokaryotes, what does that mean?
A
Two replication forks moving in opposite directions
2
Q
How many nucleotides does DNA Polymerase add per second?
A
1000
3
Q
What is a complex of multiple proteins involved in replication called?
A
Replisome
4
Q
What is pulled through the replisome?
A
DNA
5
Q
DNA replication is very accurate, what ensure high fidelity?
A
Proofreading
6
Q
What is the average mutation rate error per base inserted?
A
10^–8 to 10^–11
7
Q
Polymerase can detect mismatches though what type of bonding?
A
Hydrogen
8
Q
Proofreading occurs in what kind of microbes and organisms?
A
Prokaryotes, Eukaryotes, and viral DNA replication systems
