Chapter 4- Tissue level of organization Flashcards
4 Types of Tissue
- Epithelial Tissue
-Covers exposed surfaces
-Lines internal passageways
-Forms glands
EX: skin, tubules of kidneys - Connective Tissue
-Supports other tissues
-Transports materials
-Stores energy
EX: adipose (fats) - Muscle Tissue
-Specialized for contraction
EX: Skeletal muscle, heart muscle, and walls of hollow organs - Neural Tissue
-Carries electrical signals from one part of the body to another,
Epithelial Tissue
CHARACTERISTICS: A lot of cells, Apical (free edge) & Basal (connects cells to body. connective) surface, avascular (no blood vessels), highly mitotic
FUNCTIONS: Protection, control, permeability, nerve sensations, produce secretions (sweat, sebum, hormones)
CELL JUNCTIONS: tight junctions, gap junctions, desmosomes
Tight Junctions
Prevent passageway of fluid btwn cells
Gap Junctions
Allow ion movement btwn cells
Desmosomes
Prevent the cells from pulling apart, zipper likes attachments
*Specializations of Epithelial Cells
- Move fluids over the epithelium (protection)
- Move fluids through the epithelium (permeability)
- Produce secretions (protection and messengers)
**Polarity
- Apical surfaces
- Microvilli, Cilia - Basolateral surfaces
Microvilli
Increase absorption or secretion
Cilia
Move fluid such as mucous
Epithelia can easily be sorted into categories based on what two criteria?
Layers and Shape of cell
What 3 basic shapes do epithelia possess?
Squamous, Cuboidal, Columnar
Once you have determined the shape of the superficial cells, then you will need to look at the number of cell layers. You have two options, what are they?
Simple, Stratified
*Simple Squamous Epithelium
-one layer thick, thin & flat
LOCATION: Serous membrane, lines blood vessels and heart, alveoli of lungs
FUNCTIONS: Reduce friction; controls vessel permeability absorption and secretions
*Stratified Squamous Epithelium
-mult. layers thick, thin and flat apical surface
LOCATION: Skin, lining of mouth, throat, esophagus, anus & vagina
FUNCTIONS: Protect against physical abrasion, pathogens, and chemical attack
*Simple Cuboidal Epithelium
-one layer, as tall as they are wide
LOCATION: glands & ducts, kidney tubules
FUNCTION: secretion, but some absorption
*Transitional Epithelium
-mult. layers, varying shapes
LOCATION: Urinary tract
FUNCTION: Stretching and coiling
*Simple Columnar Epithelium
-one layer thick, taller than they are wide
LOCATION: Stomach & intestines, uterine tubes, portions of kidney tubules
FUNCTION: Protection, secretion & absorption (microvilli)
Pseudostratified Ciliated Columnar Epithelium
-mult. layers, false
LOCATION: Lines upper respiratory tract
FUNCTION: move mucus across apical surface with cilia
*Endocrine epithelial glands
- Ductless
- Secrete hormones directly into blood (or ISF)
*Exocrine epithelial glands
- Ducted
- Don’t secrete into blood but onto epithelial surfaces
**Exocrine glands modes of secretion
- Merocrine secretions
-Released by cell by exocytosis
EX: salivary glands - Apocrine secretions
-Released from cell along w/ apical surface of cell
EX: breast milk - Holocrine secretions
-Whole cell bursts
EX: sebaceous glands
Connective Tissue
FUNCTIONS: Framework, transport nutrients & dissolved gases, protect delicate organs, support other tissue, store energy, defense against pathogens
3 general categories of Connective Tissue
- Connective tissue proper
-connect and protect
EX: loose and dense connective tissue - Fluid connective tissues
-Transport
EX: blood and lymph - Supporting connective tissue
-Structural strength
EX: cartilage and bone
- Two categories of connective tissue proper
- Loose connective tissue
- Dense connective tissue
Loose connective tissue
-more ground substance. fewer fibers
Ex: Fat (adipose)
1. Areolar
Ex: collagen, elastic immune cells, fibrocytes
F: Packing material & provide an arena for immune response**
L: Dermis of skin, covered by epithelial lining of digestive, respiratory, and urinary tracts; btwn muscles, around joints, blood vessels and nerves
- Adipose
Ex: Adipocytes
F: Cushioning and insulation, energy storage
L: Subcutaneous, buttocks & breasts, padding around eyes & kidneys - Reticular
Ex: Reticularfibers
F: Structural support to some organs
L: Liver, spleen, kidneys, lymph nodes, bone marrow
Dense connective tissue
-more fibers, less ground substance Ex: tendons 1. Regular -collagen (parallel) F: Provide strength in one direction L: Tendons & ligaments
- Irregular
-collagen (not parallel)
F: Provide strength in all directions
L: Dermis, outer coating of some organs
- Fluid connective tissues
Blood- transport oxygen and carbon dioxide, immune, transport nutrients & clotting
Lymph- immune and transport leaked fluids back to the blood
- Supporting
Cartilage-
Hyaline- present in joints, respiratory tract and immature skeleton
Elastic- elastic fibers
Fibrocartilage- collagen fibers
Bone- support, internal storage of calcium & blood cell production
Connective Tissue Fibers
Collagen fibers: strength
Reticular fibers: small, branchy collagen fibers
Elastic fibers: stretch and recoil
Immune Cells
most cells - secrete histamine
Fibroblasts
Produce connective tissue fibers
Fibrocyte
Maintain connective tissue fibers
Adipocyte
Energy storage
Mesenchymal cells
Stem cells which can differentiate into fibroblasts
Mast cells
Release histamine and heparin
Macrophages
Phagocytes that engulf damaged cells or pathogens
Lymphocytes
Defense of the body; some produce antibodies
Melanocytes
Produce a brown pigment called melanin
Many allergy sufferers take antihistamines to relieve their allergy symptoms. Which cells produce the molecule that this medication blocks?
Mast cells and basophils produce histamine
Muscle tissue
Skeletal- voluntary muscles
Smooth-line hollow organs (involuntary)
Cardiac- heart (involuntary)
Nervous tissue
Neurons- communication
Glial- support neurons
Cells restore homeostasis with 2 processes
- Inflammation
2. Regeneration
** Inflammation
-The tissue’s first response to injury, triggered by trauma/ infection
Cardinal signs of inflammatory response include:
Swelling, Redness, Heat, Pain
Chemicals released by mast cells
- Prostaglandins: cause pain, lets you know you’re injured
- Histamines: vasodilation, causes a leak of blood which causes localized edema (SWELLING)
- *Increased blood circulation causes redness, heat, bringing more nutrients and oxygen; removing waste
- Heparin: limits blood clotting
- -*Histamines also cause heat, making cells replicate faster
Regeneration
Fibrocytes move to the area and produce collagen, will get remodeled to look like original tissue by mitosis
Age-related factors that affect tissue repair and structure
- Slower rate of energy consumption (metabolism)
- Hormonal alterations
- Reduced physical activity
What would account for the observed increase in cancer rates with age?
- joint pain and broken bones
- mental deterioration
- cardiovascular disease