Chapter 4: Drug interactions and Over-the Counter Drugs

Question 1

An altered or modified action or effect of a drug as a result of interaction with one or multiple drugs

Answer 1

Drug interaction

Question 2

An undesirable drug effect that ranges from mild untoward effects to severe toxic effects

Answer 2

Adverse drug reaction

Question 3

A chemical or physical reaction that occurs among two or more drugs in vitro

Answer 3

Drug incompatibility

Question 4

Do hepatic enzyme inducers increase or decrease drug metabolism? What about hepatic enzyme inhibitors?

Answer 4

Enzyme inducers increase drug metabolism (less free drug), enzyme inhibitors increase drug amounts in the blood

Question 5

What is the practice of checking serum drug levels, used primarily for drugs that have a narrow therapeutic range

Answer 5

Therapeutic drug monitoring

Question 6

When two drugs with similar action are administered, what is the drug interaction called?

Answer 6

Additive effect

Question 7

When two or more drugs are given together, one drug potentiates the other

Answer 7

Synergistic effect

Question 8

When two drugs have opposite effects or cancel the effect of the other

Answer 8

Antagonistic effect

Question 9

A drug induced skin rxn caused by exposure to sunlight

Answer 9

Photosensitivity

Question 10

How may drug categories are there according to the FDA? What are the differences between the categories

Answer 10

three categories, cat 1 drugs are safe and effective, cat 2 are unsafe in a non-prescription format, cat 3 are drugs for which there is insufficient data to judge safety/efficacy