Chapter 1:Drug Action

Question 1

Define pharmaceutic phase

Answer 1

The drug becomes a solution so it can cross the biologic membrane i.e. a pill dissolving

Question 2

The dissolving of smaller particles in the GI fluid before absorption

Answer 2

Dissolution

Question 3

The process of drug movement to achieve drug action

Answer 3

Pharmacokinetics

Question 4

List 3 ways for drugs to be absorbed into the cell

Answer 4

Passive absorption/ Active absorption/ Pinocytosis

Question 5

The percentage of the administered drug dose that reaches the systemic circulation

Answer 5

Bioavailability

Question 6

The process by which the drug becomes available to body fluids and body tissues

Answer 6

Distribution

Question 7

Drugs that are not bound to proteins

Answer 7

Free drugs (active and are what cause a response)

Question 8

The process by which the body inactivates or biotransforms drugs

Answer 8

Metabolism

Question 9

The time it takes to reach the minimum effective concentration after a drug is administered

Answer 9

Onset of action

Question 10

When a drug reaches its highest blood or plasma concentration

Answer 10

Peak action

Question 11

Drugs that affect various receptors

Answer 11

non-selective drugs

Question 12

Drugs that block a response

Answer 12

antagonists

Question 13

drugs that produce a response

Answer 13

agonists

Question 14

The margin of safety of a drug analyzing the therapeutic dose compared to the lethal dose

Answer 14

Therapeutic index

Question 15

The highest plasma concentration of a drug at a specific time

Answer 15

Peak drug level

Question 16

The lowest plasma concentration of a drug and measures the rate at which a drug is eliminated

Answer 16

Trough drug level

Question 17

Tachyphylaxis

Answer 17

a rapid decrease in the tolerance of a drug, occurs with narcotics, barbiturates, laxatives, and psychotropic agents