Chapter 4 Flashcards
What does milieu interieur mean?
Homeostasis
Who is considered the father of modern biology?
Claude Bernard
What of the ethical theories motivates medical research?
Utilitarianism
What does the Nuremberg code describe?
How medical test subjects should be treated
Voluntary consent essential
The subject should always be able to stop at any time
What ethical theory best describes the Nuremberg code?
Deontology
What did the the declaration of Helsinki update on the Nuremberg code?
Relaxed the rigidity of obtaining consent
They must obtain consent “when at all possible” but can also perform experiments if the person cannot make that descision, but a proxy gives consent
What were two well known abuse experiments discovered in the United States?
Tuskegee victims
MK Ultra
Define equipoise
Balances of forces and interests
Example: if different drugs are being tested on a group, and one of the drugs works way better, we should give that drug to re entire control group if the other drugs aren’t working
Define therapeutic research
Likely to benefit the subject
Define non-therapeutic research
Not intended/unlikely to benefit the subject
Define Phase 1
Different levels of the drug are tested.
20-80 people
Non therapeutic
Define phase 2
Tests optimal dosing, side effects
100-300
Non therapeutic
Define phase 3
Drug effectiveness
1000-3000
Define phase 4
Post approval, on-going market testing
Who believed that out descendants deserve an unplundered planet, not miracle cures?
Hans Jonas