Chapter 4 Flashcards
What is the Description of Lyme Disease?
Most cases (not all) are found in Northeast
What is the Etiology of Lyme Disease?
Carried from the host (white tailed deer, mice, raccoons, dogs, horses, etc) to humans by blacklegged ticks. Injected saliva or fecal material on skin
What is the Signs and Symptoms at Stage 1 of Lyme Disease?
Erythema chronicum migrans (ECM), but not seen in all cases. Sx include flu-like illness: fever fatigue headaches chills stiff neck muscle pain
What are the Signs and Sx of Stage 2 of Lyme Disease?
Affect the central nervous system: meningitis, nerve damage, facial palsy, etc
What are the signs and Sx of Stage 3 of Lyme Disease?
Arthritis and neurological problems. Irreversible damage
What are the diagnostic procedures for Lyme Disease?
Identification of ECM, exposure to ticks, blood tests (may take 6 weeks for antibodies to show). ELISA test detects antibodies to B. burgdorferi
Treatment for Lyme Disease
Antibiotics (Doxycycline, Amoxicillin) reduce stress ample rest
prognosis for Lyme disease
intermittent recurrence of headache, muscle pain lethargy fatigue
Prevention of Lyme disease
cover the body to prevent tick bite insect repellent, light colored clothing, tuck pants into socks, frequent inspection
West Nile Virus description
infectous disease that occurs through mosquito bite. Virus crosses blood-brain barrier causing inflammation of the brain
west nile virus etiology
bite of infected mosquito, birds are the reservoir
West Nile Virus signs/sx
range mild to severe, 80% show no symptoms
West nile virus mild Sx
fever headache body ache skin rash swollen lymph nodes
west nile virus severe Sx
mild sx with stupor disorientation, tremors convulsion coma and paralysis
west nile virus diagnostic procedures
clinical findings, blood test for antibodies (ELISA). detectable within days
West Nile virus treatment
no known cure, encourage fluids, alleviate Sx, reassurance, analgesics
West Nile virus prognosis
mild Sx last only a few days, severe sx may be permenant
West Nile virus Prevention
Insect repellent (DEET) long-sleeve clothing, pants reduce mosquito populations barriers (screens, nets windows)
Malaria description
great masquerader (presents to be many things) More world cases than US cases
Malaria etiology
infected mosquitos to humans, Protozoan infection, eventually causes destruction of RBC
Malaria Signs and Sx
Flu like
fever shaking chills headache muscle aches malaise. Nausea vomiting, diarrhea anemia jaundice
Malaria Diagnosis
Presence of protozoa parasites in the RBC on microscopic examination. Rapid blood test detect antigens
Malaria Treatment
Anti-malaria prescription medication depending on the strain of malaria
chloroquine
quinine
Malaria Prognosis
if treated promptly and correctly, prognosis is good. Potential death is diagnosis or treatment is delayed
Malaria Prevention
Avoidance of mosquitos. Pre-travel medication. Education
Anthrax Description
Acute infection of domestic animals
Three forms: Cutaneous (skin), Inhalation, Intestinal
Anthrax Etiology
Contact with animals dying of anthrax
Animal products: bone meal, animal hides
2001 Anthrax distributed to members of the U.S. Senate.
Undercooked, contaminated meat
Anthrax Symptoms Cutaneous
Raised, itchy papule at site of entry
Red papule quickly becomes a vesicle then an ulcer
Will eventually lead to septicemia, shock, death
Anthrax Sx Intestinal
Nausea, vomiting, diarrhea. Abdominal distress, fever, septicemia
Anthrax Sx Inhalation
Cold-like symptoms. Respiratory distress after 3-5 days, fever, death
All will eventually cause blood poisoning & shock
Anthrax Diagnostic Procedures
Laboratory diagnosis made by isolation of bacteria (Blood, skin lesion, respiratory secretions)
Anthrax Treatment
Penicillin/doxycycline
Broad spectrum antibiotics
Anthrax Prognosis
Without treatment 20% mortality, as high as 75% even with treatment
Anthrax Prevention
Vaccine
Education
Protective clothing
Sterilization of animal products whenever possible.
Plague description
Bubonic-bite of infected flea
Pneumonic-close contact with infected individual, respiratory secretions.
Plague Etiology
Yersinia pestis
Plague Signs and Sx
Fever, weakness, shortness of breath, chest pain, cough, pneumonia. Bloody, frothy sputum Nausea, vomiting, abdominal pain Bubonic plague Buboes
Plague Diagnostic Procedures
Blood or sputum test can confirm diagnosis
Plague Treatment
Antibiotics within 24 hours of first symptoms. Symptomatic treatment
Plague Prognosis
Without treatment pneumonic plague leads to respiratory failure, shock, death.
Plague Prevnetion/Control
Avoid contact with sick individuals.
Immediate treatment of infected to reduce transmission
E. Coli Description
Most are harmless and live in the intestinal tract. 0157:H7 produces a dangerous toxin causing serious illness. 70,000 cases each year. Eating undercooked, contaminated ground beef, contaminated lettuce, unpasteurized milk and fruit juice
E. coli Etiology
In the intestines of healthy cattle
Contamination during slaughter, present on udders
Fecal-oral route
E. coli Signs and Sx
Severe bloody diarrhea, Abdominal cramps, Resolves in 5-10 days
Complications
Children and elderly: Hemolytic uremic syndrome (HUS)
E. coli diagnostic procedures
Stool specimen tested for E. coli in all patients with bloody diarrhea
E. coli treatment
Recover 5-10 days
Supportive therapy
Rest, fluid replacement,
balanced diet. BRAT diet
E. coli prognosis
Without HUS, very good, with HUS, guarded
E. coli prevention
Cook all ground beef thoroughly (160 degrees). Pasteurized milk and juice. Prevent cross-contamination. Thorough washing of vegetables
Botulism description
Paralytic disease of the muscles
Food-borne 15%, Wound botulism 29%, Infant botulism 55%
Previously used as a warfare agent
Botulism Etiology
Clostridium botulinum
Forms spores that remain dormant until exposed to conditions supporting growth.
Botulism Signs and Sx
Nausea, vomiting, diarrhea may occur with 3-6 hours.
Dizziness, difficulty in swallowing, slurred speech, double vision, drooping eyelids, muscle weakness within 12-36 hours
Descending paralysis; death from respiratory paralysis
Botulism Treatment
Botulinum antitoxin
Respiratory assistance respiratory.
Surgical removal of the toxin-producing bacteria
Antibiotics
Botulism Prognosis
Months of recuperation may be necessary
Symptoms (fatigue and shortness of breath) may continue for years.
Botulism Prevention
Most common foods Asparagus, green beans, beets, corn Properly canned foods and strict hygienic measures High temperatures No honey for infants under one year-old
Infectous Diarrheal Disease Description
Affects children 5 years and younger
highly contagious, commonly occurring in day care centers
Infectous Diarrheal Disease Etiology
Oral fecal route
Incubation 48 hours
bacterial, viral, parasitic infections
Infectous Diarrheal Disease Signs/Sx
Diarrhea w/ or w/out blood
accompanied by nausea, vomitting, abdominal cramps, low grade fever, dehydration, electrolyte imbalance
Infectous Diarrheal Disease Diagnostic Procedures
history
physical exam
stool sample