Chapter 36 Flashcards

1
Q

What are the differential diagnosis for unilateral painful swollen leg?

A

Lymphedema, DVT, cellulitis, Baker cyst, trauma

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2
Q

What part of physical findings are present in DVT?

A

Positive Homans sign, warmth and Edema in right lower extremity

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3
Q

What are the two most commonly used noninvasive confirmatory test screening test? What is the gold standard?

A

Doppler ultrasound and IPG (impedance plethysmography); Venography

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4
Q

What should be done if suspicion of DVT is high and initial noninvasive test is negative?

A

Repeat US/IPG on date 5 and 7

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5
Q

What all plays a role in the diagnosis of DVT?

A

Pretest probability, D-dimer results, non-invasive testing

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6
Q

Why is BMP tested in patients with DVT?

A

Because IV unfractionated heparin is preferred over LMWH in the management of patients with advanced renal failure

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7
Q

What are the test we should order for DVT?

A

CBC, BMP, FOBT, PTT, PT/INR, D dimer, lower extremities Doppler ultrasound

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8
Q

How should follow up for DVT patients go?

A

Follow-up visit should be daily to monitor INR and clinical improvement

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9
Q

How should DVT patients given heparin be monitored?

A

Platelet count should be monitored on day three and day five while on heparin

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10
Q

What DVT patients should be hospitalized?

A

Massive DVT, suspicion of pulmonary embolism, risk of bleeding while on anti-coag and underlying condition requiring inpatient care

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11
Q

What are the choices for anticoagulant therapy in simple DVT’s?

A

LMWH plus warfarin or fondaparinux plus warfarin

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12
Q

What is the most common LMWH used?

A

Enoxaparin (Lovenox)

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13
Q

What should be done to screen for Heparin induced thrombocytopenia?

A

Obtain platelet count on day three and a five

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14
Q

When is warfarin added to Heparin?

A

Within 24 hours of heparin initiation

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15
Q

When is heparin discontinued?

A

After five days if INR is therapeutic (2-3) For 24-48 hours

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16
Q

When should heparin be stopped Prematurely?

A

Platelet count gets below 100,000 or reduced by 50%

17
Q

What should be monitored while on UFH?

A

PTT, therapeutic goal of 60-80

18
Q

What should be the activity for DVT?

A

Bed rest initially and ambulation once a clinical improvement

19
Q

What is the duration of longer-term were in therapy?

A

3 months: if first distal DVT or first DVT associated with reversible risk factors (surgery, OCP).
Indefinitely: if proximal DVT, pulmonary embolism, recurrent DVT
Until risk factors resolves or indefinitely: if DVT with continuing risk factors (malignancy, inherited Trombophilia)