chapter 33 Flashcards
what are the four nucleobases in DNA
adenine, cytosine, guanine, thymine
what are the four nucleobases in RNA
adenine, cytosine, guanine, uracil
which of the bases are purines
adenine, guanine
which of the bases are pyrimidines
cytosine, uracil, thymine
what is a nucleoside
base + sugar
what is a nucleotide
nucleoside + phosphate(s)
what is denaturation
disruption of base-pairing
ex: loss of a proton by the base guanine prevents base pairing with cytosine
In the interior of the helix, bases are stacked and interact with one another through
van der Waals interactions
what moves the nonpolar surfaces of the bases out of water into contact with each other
Base stacking
the most common form of DNA in the cell is
B form
A-DNA
is shorter and
wider than the B form with
the bases at an angle to
the helix axis
Z-DNA
is left-handed
and the backbone is zigzagged, accounting for the name “ZDNA”
commonly believed to provide torsional strain relief
(supercoiling) while DNA transcription occurs
stem loop
A common structural motif seen in nucleic acids, most notably RNA, is
the stem-loop, which occurs when complementary sequences in the
same strand form a double helix.
central dogma says what
DNA to RNA to proteins