Chapter 32 - Guyton Flashcards

1
Q

Pluripotent stem cells develop into either?

A

lymphoid or myeloid stem cell

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2
Q

Lymphoid stem cells develop into either?

A

T-cell and B-cell

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3
Q

Myeloid stem cells develop into?

A

eosinophil, basophil, neutrophil, monocyte (macrophage), platelets, erythrocyte

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4
Q

Main function of erythrocytes (RBCs).

A

transport hemoglobin

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5
Q

Normal hematocrit.

A

40-45%

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6
Q

Iron is transported in the blood in which form?

A

ferrous

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7
Q

Hormone released from kidney in response to low renal oxygenation.

A

erythropoietin (stimulates stem cell formation of pronormoblasts, release of reticulocytes, increase in red cell number in 5 days)

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8
Q

Where is erythropoietin produced?

A

peritubular interstitial cells of the kidney (always present in the plasma)

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9
Q

Normal Hg levels.

A

15-16 (male) gm Hg/100 mL blood, 13-14 (female) gm Hg/100 mL blood

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10
Q

Normal oxygen carrying capacity.

A

~21 ml O2/100 mL blood men, ~19 ml O2/100 mL blood women

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11
Q

If hematocrit is low, the percentage of reticulocytes will be greater/lower.

A

greater

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12
Q

Primary site of hemopoietic activity in adults.

A

bone marrow

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13
Q

Hemoglobin excreted as?

A

bilirubin

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14
Q

Plasma levels indicative of iron deficiency.

A

ferritin

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15
Q

Sites of functional iron vs. storage iron.

A

functional - RBCs, muscle, bone marrow

storage - liver, monocytes/macrophages

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